DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL4 and YML6

DIOPT Version :9

Sequence 1:	NP_524939.1	Gene:	mRpL4 / 49425	FlyBaseID:	FBgn0001995	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_013687.1	Gene:	YML6 / 854983	SGDID:	S000004487	Length:	286	Species:	Saccharomyces cerevisiae

Alignment Length:	218	Identity:	54/218 - (24%)
Similarity:	85/218 - (38%)	Gaps:	44/218 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NILKTSRQVLYPVARTFSRSGNHGNVVTEAAATVGAPP-----ATRS-PLILPQDYTDCLPVSRN 62
            |::||.:.:.|......:.:.:..|.:..||    .||     ..|| |.:.|..:   :||..:
Yeast     6 NLVKTLQSIRYQATTATAHAESTLNPLPNAA----IPPKYALVTVRSFPSLEPLTF---VPVPTS 63

  Fly    63 TARQAWIENTDAVAERKVGLIELHPDVFAAQPRVDIIQENVEWQSKYRYVSMAHTKTRAEVRGGG 127
            |.                          ||..|.||:...|.:::..|.|..::...|:|.....
Yeast    64 TV--------------------------AAPLRRDILWRAVVYENDNRRVGASNPPGRSENGFSR 102

  Fly   128 RKPWPQKGGGRARHGSLRSPMLKGGGVVHGPRSPTTHFYMLPFYKRVLGLTSTLSVKLAQDDLHI 192
            ||..||||.||||.|...||....||......:|..:...||.....:...:.||.:.....|.:
Yeast   103 RKLMPQKGSGRARVGDANSPTRHNGGRALARTAPNDYTTELPSKVYSMAFNNALSHQYKSGKLFV 167

  Fly   193 I--DNVDI--PTGDAEFLK-DLI 210
            |  :.||:  ||.:.:..: ||:
Yeast   168 IGGEKVDLISPTPELDLNRLDLV 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL4	NP_524939.1	Ribosomal_L4	83..274	CDD:278970	38/133 (29%)
YML6	NP_013687.1	Ribosomal_L4	58..272	CDD:395455	41/159 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345814
Domainoid	1	1.000	45	1.000	Domainoid score	I3121
eggNOG	1	0.900	-	-		E1_COG0088
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003002
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101056
Panther	1	1.100	-	-	LDO	PTHR10746
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1141
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770