DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL4 and Rpl4

DIOPT Version :9

Sequence 1:	NP_524939.1	Gene:	mRpL4 / 49425	FlyBaseID:	FBgn0001995	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_077174.1	Gene:	Rpl4 / 67891	MGIID:	1915141	Length:	419	Species:	Mus musculus

Alignment Length:	266	Identity:	61/266 - (22%)
Similarity:	100/266 - (37%)	Gaps:	81/266 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 PDVFAAQPRVDI---IQENVEWQSKYRYV--SMAHTKTRAEVRGGGR--KPWPQ-KGGGRARHG- 142
            |.||.|..|.||   :..|:...::..|.  .:|..:|.||..|.||  ...|: :|||..|.|
Mouse    25 PAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQ 89

  Fly   143 SLRSPMLKGGGVVHGPRSPTTHFYMLPFYKRV------LGLTSTLSVK----LAQDDLHIIDNV- 196
            .....|.:||.:.    :||..:..  :::||      ..:.|.|:..    |.....|.|:.|
Mouse    90 GAFGNMCRGGRMF----APTKTWRR--WHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVP 148

  Fly   197 DIP------------TGDA-EFLKDLIAERNW----------------------------GPSVL 220
            ::|            |.:| :.||.|.|   |                            ||.:
Mouse   149 ELPLVVEDKVEGYKKTKEAVQLLKKLKA---WNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCI- 209

  Fly   221 IVDEDHMFPANICQASDDLGYVNLMPTFGLNVYSMLKHDTL----VLTVAAVKHLEQRLLYQLNR 281
            |.:||:    .|.:|..::..:.|:....||:..:.....:    :.|.:|.:.|::  ||...|
Mouse   210 IYNEDN----GIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDE--LYGTWR 268

  Fly   282 NDAASK 287
            ..|:.|
Mouse   269 KAASLK 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL4	NP_524939.1	Ribosomal_L4	83..274	CDD:278970	56/251 (22%)
Rpl4	NP_077174.1	PTZ00428	2..352	CDD:185611	61/266 (23%)
Rpl4	NP_077174.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..419
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0088
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900