DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL4 and Mrpl4

DIOPT Version :9

Sequence 1:	NP_524939.1	Gene:	mRpL4 / 49425	FlyBaseID:	FBgn0001995	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001344828.1	Gene:	Mrpl4 / 66163	MGIID:	2137210	Length:	300	Species:	Mus musculus

Alignment Length:	245	Identity:	107/245 - (43%)
Similarity:	144/245 - (58%)	Gaps:	34/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LPVSRNTARQAWIENTDAVAERKVGLIELHPDVFAAQPRVDIIQENVEWQSKYRYVSMAHTKTRA 121
            :||.|... |||:|:.....:.::||.||||||||..||:||:.:...||..:|.:|.|:|||||
Mouse    55 IPVHRRPV-QAWVESLRGFEQERIGLAELHPDVFATAPRLDIVHQVAIWQRNFRRISYANTKTRA 118

  Fly   122 EVRGGGRKPWPQKGGGRARHGS---------LRS----------PMLKGGGVVHGPRSPTTHFYM 167
            |:.             ...|.:         |||          ..:..|||.||||.||:::||
Mouse   119 ELL-------------NITHSNTLCQPSSKFLRSQTSGDTNTSYATVPAGGVAHGPRGPTSYYYM 170

  Fly   168 LPFYKRVLGLTSTLSVKLAQDDLHIIDNVDIPTGDAEFLKDLIAERNWGPSVLIVDEDH-MFPAN 231
            ||...|.|||...|:|||.||||||:|::::||.|.::|.:|...|:||.|||:||..| ..|.|
Mouse   171 LPMKVRALGLKVALTVKLMQDDLHIVDSLELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKN 235

  Fly   232 ICQASDDLGYVNLMPTFGLNVYSMLKHDTLVLTVAAVKHLEQRLLYQLNR 281
            :..|:..|...||:|..||||||||||.|||||:.:|..||.:||:|.:|
Mouse   236 VVAATSGLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSR 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL4	NP_524939.1	Ribosomal_L4	83..274	CDD:278970	94/210 (45%)
Mrpl4	NP_001344828.1	Ribosomal_L4	81..278	CDD:306944	94/209 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848448
Domainoid	1	1.000	235	1.000	Domainoid score	I2360
eggNOG	1	0.900	-	-		E1_COG0088
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32286
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3107
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52318
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003002
OrthoInspector	1	1.000	-	-		oto93425
orthoMCL	1	0.900	-	-		OOG6_101056
Panther	1	1.100	-	-	LDO	PTHR10746
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1141
SonicParanoid	1	1.000	-	-		X3343
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790