Protein Alignment SERCA and YPK9

DIOPT Version :9

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: NP_014934.1
• Gene: YPK9 / 854466
• SGDID: S000005817
• Length: 1472
• Species: Saccharomyces cerevisiae
• Alignment Length: 1192
• Identity: 232/1192 - (19%)
• Similarity: 412/1192 - (34%)
• Gaps: 397/1192 - (33%)

  Fly    19 DPE--------RGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKILL----LAAII 71
            ||:        .|||....:..:..:|.|::         .|.::...::|...:|    :..:.
Yeast   449 DPDWVDLSTVSNGLTKGVQEDRELAFGKNQI---------NLRMKTTSEILFNEVLHPFYVFQVF 504

  Fly    72 SFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKSG 136
            |.:|...:|:      :.....|.||.:.:....:.:::.....:..:..:..:: :|:| ||..
Yeast   505 SIILWGIDEY------YYYAACIFLISVLSIFDSLNEQKKVSRNLAEMSHFHCDV-RVLR-DKFW 561

  Fly   137 IQKVRAKEIVPGDLVEVSVGDK----IPADIRITHIYSTTLRIDQSILTGESVSVIKH------- 190
             ..:.:.|:||||:.|||  |.    :|.|   :.:.|:...:::|:||||||.|.|.
Yeast   562 -TTISSSELVPGDIYEVS--DPNITILPCD---SILLSSDCIVNESMLTGESVPVSKFPATEETM 620

  Fly   191 ---TDAIPDPRAVNQDKKNILFSGTN-----VAAGK--ARGVVIGTGLSTAIGKIRTEMSETEEI 245
               .|.....:..:...|:.|::|||     :|.|:  |..:|:.||.||..|.:...|...:
Yeast   621 YQLCDDFQSTQISSFVSKSFLYNGTNIIRARIAPGQTAALAMVVRTGFSTTKGSLVRSMVFPK-- 683

  Fly   246 KTPLQQKLDEFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKI----------AV 300
            .|..:...|.|  :....:|:|.:..:.::                .:.:.|:          |:
Yeast   684 PTGFKFYRDSF--KYIGFMSLIAIFGFCVS----------------CVQFIKLGLDKKTMILRAL 730

  Fly   301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV-- 363
            .:....:|..|||.:|........|:.:|.....|...:...|...|:|.|||||||.:.:.|
Yeast   731 DIITIVVPPALPATLTIGTNFALSRLKEKGIFCISPTRLNISGKIDVMCFDKTGTLTEDGLDVLG 795

  Fly   364 ----------SRMF---------IFDKVEGND-SSFLEFEMTGSTYEPIGEVFLNGQRIKAADYD 408
                      .:.|         :|.|...|| ||.|:|:.......     .|....:::.|.:
Yeast   796 VQISEPNGVRGQKFGELLSDIRQVFPKFSLNDCSSPLDFKSRNFFMS-----LLTCHSLRSVDGN 855

  Fly   409 TLQELSTICIMCNDSAIDYNEF------------KQAFEKVGEA-------TETALIVLA----- 449
            .|.:           .:|:..|            |:||..:.|.       .|.:.|:.|
Yeast   856 LLGD-----------PLDFKMFQFTGWSFEEDFQKRAFHSLYEGRHEDDVFPENSEIIPAVVHPD 909

  Fly   450 --EKLNSFSVNK--------------SGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYC 498
              .:.|:|:.|.              |.|.|.|..:....: :..|.
Yeast   910 SNNRENTFTDNDPHNFLGVVRSFEFLSELRRMSVIVKTNND-DVYWS------------------ 955

  Fly   499 TPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCL- 562
                          |.|||||.:.|.|.           .|.|.|..          .:.|||.
Yeast   956 --------------FTKGAPEVISEICN-----------KSTLPADF----------EEVLRCYT 985

  Fly   563 -----ALAVADSPMKPDEMDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVI 622
                 .:|.|...:..............:.|.||.|:|.:...:..:||..:::...:.|.||.|
Yeast   986 HNGYRVIACAGKTLPKRTWLYSQKVSREEVESNLEFLGFIIFQNKLKKETSETLKSLQDANIRTI 1050

  Fly   623 VITGDNKATAEAICRRIGVF---------AEDEDTTGK--------------------------- 651
            :.||||..||.::.|..|:.         ..|....|:
Yeast  1051 MCTGDNILTAISVGREAGLIQCSRVYVPSINDTPLHGEPVIVWRDVNEPDKILDTKTLKPVKLGN 1115

  Fly   652 -------------SYSG-------REFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNE 696
                         :.||       |:.:::........:..|.:::|:.|..|.:::..||.::.
Yeast  1116 NSVESLRECNYTLAVSGDVFRLLFRDENEIPEEYLNEILLNSSIYARMSPDEKHELMIQLQKLDY 1180

  Fly   697 ISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRA--------- 752
            .....|||.||..|||.|::||::..  |.|..||.......|.|.::..:.||||
Yeast  1181 TVGFCGDGANDCGALKAADVGISLSE--AEASVAAPFTSKIFNISCVLDVIREGRAALVTSFACF 1243

  Fly   753 ----IYNNMKQFIR----YLISSNIGEVVSIFLTAALGLPEALIPVQLLW-------------VN 796
                :|:.: |||.    |...||:|:...:::...|.:|   |.:.:.|             .|
Yeast  1244 QYMSLYSAI-QFITITILYSRGSNLGDFQFLYIDLLLIVP---IAICMSWSKSYEKIDKKRPSAN 1304

  Fly   797 LVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVGAATVGAAAWWFVFSDE 861
            ||:                     |:.....|||.:|.|.:..|.             |.:..
Yeast  1305 LVS---------------------PKILVPLLISVFLVFLFQFIP-------------WIIVQ-- 1333

  Fly   862 GPKLSYWQLTHHLSCLGGGDEFKGVDCKI---------------------FSDPHAMTMALSVLV 905
              |:| |.:.   ..:||.|..:..|..:                     :.:|.:......|.:
Yeast  1334 --KMS-WYIK---PIVGGDDAVQSSDNTVLFFVSNFQYILTAIVLSVGPPYREPMSKNFEFIVDI 1392

  Fly   906 TIE-----MLNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQV-TPLSA 964
            |:.     :|..:::.|....::.:.|..|         |||: |:|::| :|:...|: .|.|.
Yeast  1393 TVSIGASLLLMTLDTESYLGKMLQLTPISN---------SFTM-FIIVWV-ILNYYAQLYIPPSI 1446

  Fly   965 EEWITVMKFSIPV-VLLDETLK 985
            :.|:...|.|... :|:.|.:|
Yeast  1447 KGWLKKKKSSKKYKLLIQEEMK 1468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	232/1192 (19%)
YPK9	NP_014934.1	P-ATPase-V	307..1431	CDD:273738	221/1152 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910