Protein Alignment SERCA and atp2a3

DIOPT Version :9

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: NP_001072333.1
• Gene: atp2a3 / 779786
• XenbaseID: XB-GENE-949483
• Length: 1033
• Species: Xenopus tropicalis
• Alignment Length: 994
• Identity: 696/994 - (70%)
• Similarity: 820/994 - (82%)
• Gaps: 0/994 - (0%)

  Fly     1 MEDGHSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKIL 65
            |:..|:|||.:.|..|..:...||:.:|::.:::|||.||||.|||||:|:||||||:||||:||
 Frog     1 MDSAHAKTVSEVLRHFEVNENCGLSSEQVRRSREKYGLNELPAEEGKSLWELVLEQFEDLLVRIL 65

  Fly    66 LLAAIISFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVV 130
            ||||.:||:||.|||.|||.||||||:||::||:.||.||||||||||||||||||||||||||:
 Frog    66 LLAAFVSFILAWFEEGEETTTAFVEPIVIIMILVINAFVGVWQERNAESAIEALKEYEPEMGKVI 130

  Fly   131 RQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIP 195
            |.|:||:|::||::|||||:|||:||||:|||||||.|.|||||:|||||||||||||||||.||
 Frog   131 RGDRSGVQRIRARDIVPGDIVEVAVGDKVPADIRITEIRSTTLRVDQSILTGESVSVIKHTDPIP 195

  Fly   196 DPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQL 260
            |||||||||||:||||||:|||||.|:||.||:.|.|||||.:|..||..||||||||||||:||
 Frog   196 DPRAVNQDKKNMLFSGTNIAAGKAVGIVIATGIYTEIGKIRNQMVATEPEKTPLQQKLDEFGQQL 260

  Fly   261 SKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRR 325
            |||||:||||||.|||||||||.|||||.:|||||||||||||||||||||||||||||||||||
 Frog   261 SKVISLICVAVWVINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRR 325

  Fly   326 MAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEMTGSTYE 390
            ||||||||||||||||||||||||||||||||||||||||||:.:|:||.:.||.||.:|||||.
 Frog   326 MAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFVIEKIEGVNCSFHEFSITGSTYA 390

  Fly   391 PIGEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSF 455
            |:|:|..:.|.:....||.|.||:|||.:||||::|:||.|..:|||||||||||..|.||:|.|
 Frog   391 PVGQVLKDEQPVNCGQYDGLVELATICALCNDSSLDFNESKGVYEKVGEATETALTCLVEKMNVF 455

  Fly   456 SVNKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEG 520
            :.:.|.|.:...|.||...|:...|||.||||||||||||.||..:..:...:..|:|||||||.
 Frog   456 NTDLSTLSKVERANACNSVIKKLMKKECTLEFSRDRKSMSVYCNSVAPNSGQSASKMFVKGAPES 520

  Fly   521 VLERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFY 585
            |:|||.:.|||:||:|||.:.:.||::....:|||.|||||||||..|.|.|.::|.|.|||||.
 Frog   521 VIERCNYVRVGSTKLPLTPSAREKIMSKIRDWGTGMDTLRCLALATRDVPPKLEDMQLDDSTKFI 585

  Fly   586 QYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFAEDEDTTG 650
            .||.||||||.|||||||||||..||..|:.|||:||:||||||.||.||||:||:|::.||.|.
 Frog   586 NYETNLTFVGCVGMLDPPRKEVSISIELCKRAGIKVIMITGDNKGTAVAICRKIGIFSDYEDITD 650

  Fly   651 KSYSGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAE 715
            |:|:|||||||.|..|:.|...:|.|:||||.|||||||:|||.:||:|||||||||||||||||
 Frog   651 KAYTGREFDDLPPERQREACRSARCFARVEPAHKSKIVEYLQSYSEITAMTGDGVNDAPALKKAE 715

  Fly   716 IGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAA 780
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:||||.|||||.
 Frog   716 IGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI 780

  Fly   781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVG 845
            |||||||||||||||||||||||||||||||||||||||.||...|.||||||||||:|||.|||
 Frog   781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPREPLISGWLFFRYLAIGVYVG 845

  Fly   846 AATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEML 910
            .||||||.|||::.::||:::::||.|.:.|......|.|:||.:|...:..||||||||||||.
 Frog   846 LATVGAATWWFLYDEDGPQVTFYQLRHFMKCTSDNPLFSGIDCDVFESRYPTTMALSVLVTIEMC 910

  Fly   911 NAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSI 975
            ||:|||||||||:.||||.|:||:|::.:|..|||:|||:..:..||||.||:..:|:.|:|.|:
 Frog   911 NALNSLSENQSLLRMPPWLNIWLLGAIIMSMALHFLILYIKPMPLVFQVIPLNWSQWVVVLKISL 975

  Fly   976 PVVLLDETLKFVARKIADG 994
            ||:||||.||:::|...||
 Frog   976 PVILLDEGLKYISRHHLDG 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	692/983 (70%)
atp2a3	NP_001072333.1	P-type_ATPase_SERCA	5..989	CDD:319778	692/983 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	352	1.000	Domainoid score	I1001
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1462	1.000	Inparanoid score	I112
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100699at2759
OrthoFinder	1	1.000	-	-		FOG0000231
OrthoInspector	1	1.000	-	-		otm49022
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X745
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060