Protein Alignment SERCA and atp13a3

DIOPT Version :9

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: XP_009304446.2
• Gene: atp13a3 / 572029
• ZFINID: ZDB-GENE-120521-1
• Length: 1225
• Species: Danio rerio
• Alignment Length: 1183
• Identity: 238/1183 - (20%)
• Similarity: 433/1183 - (36%)
• Gaps: 407/1183 - (34%)

  Fly    29 IKANQKKY-----GPNELPTEEGKSIWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEETFTAF 88
            :..||::|     |.||:..:. .|:::|::::    ::....:..:.|.||...:|:.....|.
Zfish   178 LNKNQQEYRRFFFGLNEIDVKV-PSLFKLLIKE----VLNPFYIFQLFSVVLWCTDEYYYYAMAI 237

  Fly    89 VEPLVILLILIANAVVGVWQERNAESAIEALKEY---------EPEMGKVVRQDKSGIQKVRAKE 144
            |   |:..|.||.::..:            .|:|         ...:...|.:.:|..::..:.:
Zfish   238 V---VMSFISIATSLYTI------------KKQYVMLHDMVATHSTVRVTVCRGESETEEALSTD 287

  Fly   145 IVPGDLVEV-SVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPR---------- 198
            :||||::.: |.|..:|.|..:  |..|.: :::|:||||||.|.| || :|:|.
Zfish   288 LVPGDVIVIPSNGTIMPCDAVL--ICGTCI-VNESMLTGESVPVTK-TD-LPNPERDKKGSDGDQ 347

  Fly   199 --AVNQDKKNILFSGTNVAAGK------ARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDE 255
              :..:.|::.||.||||...:      .:.||:.||.|||.|::         |::.|..|..:
Zfish   348 IYSTEEHKRHTLFCGTNVIQTRYYTGEMVKAVVVRTGFSTAKGQL---------IRSILYPKPTD 403

  Fly   256 FGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKI----------------AVALAV 304
            |.......:.::|:..                 :...::.:.:                ::.:..
Zfish   404 FKLYRDAYLFLLCLVA-----------------VASVVFIYSLVMKILNQEPVKEIIVKSLDIIT 451

  Fly   305 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIF 369
            ..:|..|||.:|..:....||:.|......|...:...|..:::|.|||||||.:.:.   |:..
Zfish   452 ITVPPALPAAMTAGIVYAQRRLRKVGIFSISPQRINICGQLNLVCFDKTGTLTEDGLD---MWGI 513

  Fly   370 DKVEGNDSSF-----------------------------LEFEMTG-----STYEPIGEVFLNGQ 400
            .:||  ||.|                             :|.:::|     ..:|..|.:.:...
Zfish   514 QRVE--DSRFQHSEERADDKSLVTSRFVSCMATCHSLTKIEGQLSGDPLDLKMFEATGWILVEAT 576

  Fly   401 RIKAADYDTLQ--------ELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSFSV 457
            ..:.|.:|.::        :|....::..:..::.:|       :.|.:.:.:|.:..:. |||
Zfish   577 EEETAHHDRIELTYVKPPNQLLPPPVISPEQDMELSE-------LYELSASYMIGIVRQF-SFS- 632

  Fly   458 NKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVL 522
              |.|.|.|..:...||                 :.|.:|                :|||||.|.
Zfish   633 --SALQRMSVVVRQIGE-----------------RRMDAY----------------LKGAPEVVA 662

  Fly   523 ERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFY-- 585
            ..|....|...        .|::|....:.|     .|.:|||         ...|.....|:
Zfish   663 SLCKKESVPED--------FAEVLEDYTKQG-----FRVIALA---------HRRLESKLTFHKV 705

  Fly   586 ------QYEVNLTFVGVVGMLDPPRKE---VFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGV 641
                  |.|.|:.|:|::.|.:..:.|   |.|.:   |.|.||.:::||||..||.::.|..|:
Zfish   706 QNINRDQIEKNMDFLGLIVMQNKLKTETPGVLDDL---RRANIRTVMVTGDNMLTAISVARDCGM 767

  Fly   642 --------------------------FAE-------------------------DEDTTGKSY-- 653
                                      :|:                         ||..:.:.|
Zfish   768 IQPLDLVIIADAVPPKDGQAAKINWHYADKPSKHSNKPTKLEEVEIILEDGHSVDESRSQEQYHF 832

  Fly   654 --SGREF----DDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALK 712
              ||:.|    :......|| .|....:|:|:.|..|:::||.|:|::....|.|||.||..|||
Zfish   833 AMSGKSFAVIIEHFQDLLQK-LVLHGTVFARMAPDQKTQLVETLESVDYFVGMCGDGANDCGALK 896

  Fly   713 KAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRA-------IYNNMKQF---------I 761
            :|..||::..  ..|..|:.......:.:.:.:.:.||||       ::..|..:         :
Zfish   897 RAHAGISLSE--LEASVASPFTSTTPSITCVPNLIREGRAALITSFCVFKFMALYSIIQCLSVAL 959

  Fly   762 RYLISSNIGEVVSIFLTAALGLPEALI----PVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPR 822
            .|.|.||:|:...:|:..|:.|   ||    .:...|..||.                  .:||
Zfish   960 LYSIGSNLGDFQFLFIDMAIIL---LIVFTMSLNSAWKELVA------------------RRPP- 1002

  Fly   823 KADEGLISGWLFFRYM-----AIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHHL----SCLG 878
               .||:||.|.|..:     .:.|.:.|..:.....|:    ..|......|.||:    :..|
Zfish  1003 ---SGLVSGPLLFSVLTQILICLAFQIIAFLLIQRLDWY----SKPDFYNCSLPHHMNNYSNSTG 1060

  Fly   879 GGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNS----LSENQSLIT-----------MPPW 928
            ..:|                         .::|.:|:    :|..|.||.           .|.:
Zfish  1061 TKEE-------------------------NIVNDVNTTLFFISSFQYLIVAIVFSKGKPFRQPSY 1100

  Fly   929 CNLW--LIGSMALSFTLHFVILYVDVLSTVFQ-----VTPLSAEEWITVMKFSIPVVLLDETLKF 986
            .| |  ::.::.|...:.|::.:  .:|.:::     ..|||   |    :.|:.:::|..|:..
Zfish  1101 KN-WPFVLSALILVIFMFFIMFF--PISGIYKFLELVCVPLS---W----RVSMVIIILANTIVS 1155

  Fly   987 VARKIADGESPIY 999
            |   |.:|...:|
Zfish  1156 V---IIEGGIDMY 1165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	235/1171 (20%)
atp13a3	XP_009304446.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910