Protein Alignment SERCA and SPoCk

DIOPT Version :10

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Alignment Length: 1042
• Identity: 314/1042 - (30%)
• Similarity: 495/1042 - (47%)
• Gaps: 192/1042 - (18%)

  Fly    19 DPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEE 83
            |...||...:.|...|..|.|||........|:..:|||.:.|:.:||.:|::|.::..|::
  Fly   126 DVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNPLILLLLGSALVSVIMKQFDD--- 187

  Fly    84 TFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKSGIQKVRAKEIVPG 148
                .|...:.:||::..|.:   ||..:|.::|.||:..|.....:|:.:  :....|:|:|||
  Fly   188 ----AVSITIAILIVVTVAFI---QEYRSEKSLEELKKLVPPECHCLREGR--LDTFLARELVPG 243

  Fly   149 DLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPRAV--NQDKKNILFSG 211
            |:|.::|||::|||:|:  ..:..|.||:|..|||:....|.||.:.:...|  :.:.|||.|.|
  Fly   244 DIVHLNVGDRVPADVRL--FEAVDLSIDESSFTGETEPARKITDVLLNNTNVKDHSNMKNIAFMG 306

  Fly   212 TNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLS----KVISVICVAVW 272
            |.|..|..:|:|:.||..:..|::...|...|..|||||:.:|..|.|||    .:|.||.:.
  Fly   307 TLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIMLL-- 369

  Fly   273 AINIGHFNDPAHGGSWIKG--AIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335
                          .|::|  ....|.|:|:|||||||||||.|:|..||||..||||:|:||:.
  Fly   370 --------------GWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKK 420

  Fly   336 LPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEMTGSTYEPIGEVFL--- 397
            ||:||||||.:|||||||||||.|:|:.:.:...|....        ::||:.|...||:.:
  Fly   421 LPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMA--------DVTGAGYNDQGEIHIRHC 477

  Fly   398 NGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSFSVNKSGL 462
            |...:...:...|.|:..:|         .|.:.|....:|:.||.||:.:|.|...::..::
  Fly   478 NNVEMAKTNITNLLEIGAVC---------NNAYIQNGTLLGQPTEGALVAVAMKNGMYATAEN-- 531

  Fly   463 DRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCTH 527
                            :.:.....||.::|.|:..|  :...........|.|||.|.:|.:||.
  Fly   532 ----------------YVRIQEYPFSSEQKMMAVKC--IHKYNNNKEEIFFAKGALETLLPQCTK 578

  Fly   528 ARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFYQYEVNLT 592
            .:.||..||||...:|:.||  ..|..||..||.||||...|..                  :|.
  Fly   579 YQFGTQTVPLTKQNEAEFLA--EAYEIGRKGLRVLALAKGRSMQ------------------DLI 623

  Fly   593 FVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAI--CRR----------------- 638
            :.|:||:.||||..|.:||.....:|:||.::|||.:.||.||  .||
  Fly   624 YCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGG 688

  Fly   639 ---------------------------------------IGVFAEDEDTT-GKSYSGREFDDLSP 663
                                                   ||:     ||. .::.||:|.|.::.
  Fly   689 VPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGI-----DTIHHQTLSGQEMDQMNE 748

  Fly   664 TEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMG-SGTAVA 727
            .:.........:|.||.|:||.:||:.||....|..||||||||..|||||:|||||| :||.|.
  Fly   749 HQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVC 813

  Fly   728 KSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQL 792
            |.||:|:|.:|:|.:|::|:|||:.|:.|::.|:|:.:|::|..:..|.|...:.:...|..:|:
  Fly   814 KEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQI 878

  Fly   793 LWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVGAATVGAAAWWFV 857
            ||:|::.||.||.:||..|.|.|::::.||...:.:|:     :.:.:...:.|:.:.....| |
  Fly   879 LWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMIT-----KSVVVNVLLSASIIVLGTLW-V 937

  Fly   858 FSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLSENQSL 922
            |..|                       ..|..:.......||..:..|..:|.||::..|:.:|:
  Fly   938 FQRE-----------------------MADGTLGKTKRDTTMTFTCFVFFDMFNALSCRSQTKSV 979

  Fly   923 ITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSIPVVLLDETLKFV 987
            .|:....|...:.::|.|.....:::|...|..|||...|:..:...::..:..|:::.|..|:.
  Fly   980 FTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLVSLTSSVLVVSEIKKWF 1044

  Fly   988 AR 989
            .|
  Fly  1045 ER 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	313/1040 (30%)
SPoCk	NP_001262220.1	P-type_ATPase_SPCA	139..1042	CDD:319779	308/1023 (30%)