Protein Alignment SERCA and atp1a1

DIOPT Version :9

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: NP_989407.1
• Gene: atp1a1 / 395044
• XenbaseID: XB-GENE-484831
• Length: 1023
• Species: Xenopus tropicalis
• Alignment Length: 1074
• Identity: 325/1074 - (30%)
• Similarity: 506/1074 - (47%)
• Gaps: 179/1074 - (16%)

  Fly     1 MEDGHSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKIL 65
            ||| |..::::....||||.:|||:..:......:.|||.|........|.....|.......:|
 Frog    41 MED-HKLSLDELHRKFGTDMQRGLSTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLL 104

  Fly    66 LLAAIISFV---LALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMG 127
            .:.||:.|:   :....|.|.|.......:|:..::|.......:||..:...:|:.|...|:..
 Frog   105 WIGAILCFLAYGITAATEEEPTNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQA 169

  Fly   128 KVVRQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTD 192
            .|:|..:.  ..:.|:::|.||||||..||:||||:||  |.:...::|.|.|||||....:
 Frog   170 LVIRNGEK--LSINAEDVVLGDLVEVKGGDRIPADVRI--ISAHGCKVDNSSLTGESEPQTR--- 227

  Fly   193 AIPDPRAVNQ---DKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLD 254
               .|...|:   :.:||.|..||...|.|||||:.||..|.:|:|.|..|..|..:||:..:::
 Frog   228 ---SPDFTNENPLETRNIAFFSTNCVEGTARGVVVNTGDRTVMGRIATLASGLEGGRTPIAIEIE 289

  Fly   255 EFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCL 319
            .|...::.|...:.|:.:.:::      ....:|::..|:    .:.:.||.:||||.|.:|.||
 Frog   290 HFIHIITGVAVFLGVSFFILSL------ILQYTWLEAVIF----LIGIIVANVPEGLLATVTVCL 344

  Fly   320 ALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEM 384
            .|..:|||:||.:|::|.:|||||.||.||||||||||.|:|:|:.|:..:::...|::
 Frog   345 TLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTT------ 403

  Fly   385 TGSTYEPIGEVFLNGQRIKAADYD----TLQELSTICIMCNDSAIDYNEFKQAFEK---VGEATE 442
                           :....|.:|    |...||.:..:||.:.....:......|   .|:|:|
 Frog   404 ---------------ENQSGASFDKSSPTWTALSRVAGLCNRAVFQAGQENTPILKRDVAGDASE 453

  Fly   443 TALIVLAEKLNSFSVNKSGLDRRSAAIACRG---EIETKWKKEFTLEFSRDRK---SMSSYCTPL 501
            :||:...|                   .|.|   ::..|..|...:.|:...|   |:.....|.
 Frog   454 SALLKCIE-------------------LCCGSVRDMREKNPKVAEIPFNSTNKYQLSVHKNANPS 499

  Fly   502 KASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALTGQY----GTGRDTLRCL 562
            ::..:     |.:|||||.:|:||:...:...:.||...||.   |....|    |.|...|...
 Frog   500 ESRYI-----LVMKGAPERILDRCSTIVLQGKEQPLDEELKD---AFQNAYLELGGLGERVLGFC 556

  Fly   563 ALAVADSPMKPDEMDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGD 627
            .||::|... ||..........:..| ||.|||::.|:||||..|.|::.:||:|||:||::|||
 Frog   557 HLALSDDQF-PDGFQFDTEEVNFPTE-NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGD 619

  Fly   628 NKATAEAICRRIGVFAEDEDTTGKSYSGR---EFDDLSPTEQKAAVARSR--------------- 674
            :..||:||.:.:|:.:|..:|. :..:.|   ..:.::|.:.||.|....
 Frog   620 HPITAKAIAKGVGIISEGNETV-EDIAARLNIPVNQVNPRDAKACVIHGSDLKDMAQEQIDDILK 683

  Fly   675 -----LFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEM 733
                 :|:|..||.|..|||..|....|.|:|||||||:||||||:|||||| :|:.|:|.||:|
 Frog   684 HHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGIAGSDVSKQAADM 748

  Fly   734 VLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVS--IFLTAALGLPEALIPVQLLWVN 796
            :|.||||:|||:.|||||.|::|:|:.|.|.::|||.|:..  ||:.|.:.||  |..|.:|.::
 Frog   749 ILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIVANIPLP--LGTVTILCID 811

  Fly   797 LVTDGLPATALGFNPPDLDIMEKPPR--KAD----EGLISGWLFFRYMAIGFYVGAATVGAAAWW 855
            |.||.:||.:|.:...:.|||::.||  |.|    |.|||       ||.|.......:|....:
 Frog   812 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLIS-------MAYGQIGMIQALGGFFTY 869

  Fly   856 FVFSDEGPKLSYWQLTHHLSCLG----------------GGDEFKGVDCKI--FSDPHAMTMALS 902
            ||...|...|. |.|      ||                .|.::.....||  |:...|..:::.
 Frog   870 FVILAENGFLP-WTL------LGIRVNWDDRWNNDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIV 927

  Fly   903 VLVTIEML---NAMNSL----SENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVT 960
            |:...:::   ...||:    .:|:.||       ..|....||:..|.    |...:....::.
 Frog   928 VVQWADLIICKTRRNSVFQQGMKNKILI-------FGLFEETALAAFLS----YCPGMDVALRMY 981

  Fly   961 PLSAEEWITVMKFSIPVVLLDETLKFVARKIADG 994
            ||....|.....:|:.:.:.||..|.:.|:...|
 Frog   982 PLKPTWWFCAFPYSLLIFIYDEVRKLIIRRSPGG 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	320/1063 (30%)
atp1a1	NP_989407.1	ATPase-IIC_X-K	32..1023	CDD:273445	325/1074 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100699at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010