Protein Alignment SERCA and pmr1

DIOPT Version :10

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: NP_595098.1
• Gene: pmr1 / 2540383
• PomBaseID: SPBC31E1.02C
• Length: 899
• Species: Schizosaccharomyces pombe
• Alignment Length: 1005
• Identity: 329/1005 - (32%)
• Similarity: 519/1005 - (51%)
• Gaps: 151/1005 - (15%)

  Fly     8 TVEQSLNFFGTDPERGL-TLDQIKANQKKYGPNELPTEEGKSIWQLVLEQF-DDLLVKILLLAAI 70
            :|||:.....||...|| :|.:|....|.:|.|:|..|:.:::....|:|| .|.|:.:|..::.
pombe     9 SVEQTCADLETDMYNGLSSLQEITRRNKVHGDNDLKVEDEENMVVQFLKQFVKDPLILLLFASSA 73

  Fly    71 ISFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKS 135
            ||..|...:          :.:.|.|.::....||..||..:|.:::||....|....|:|..|:
pombe    74 ISVTLGNID----------DAISIALAIVIVVTVGFVQEYRSEQSLKALNNLVPHYCNVIRSGKT 128

  Fly   136 GIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPRAV 200
              :.:.|.::||||||.:.:||::|||:||  :.:|.|.||:|.||||:....|.::||....::
pombe   129 --EHIVASKLVPGDLVILQIGDRVPADLRI--VEATELEIDESNLTGENSPRKKSSEAISSNISL 189

  Fly   201 NQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVIS 265
            . ::.||.|.||.|..|..||:|:.||..|..|::...|.:||:.|||||..:|:.|:||| :||
pombe   190 T-ERNNIAFMGTLVRHGHGRGIVVATGSDTEFGRVFLTMQQTEKPKTPLQNSMDDLGKQLS-LIS 252

  Fly   266 VICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKN 330
            :|.:|| .:.:|.|    .|.:|::    ...|.|:|||||||||||.::|..||||..||:||.
pombe   253 LIGIAV-IVLVGFF----QGKNWLE----MLTIGVSLAVAAIPEGLPIIVTVTLALGVLRMSKKR 308

  Fly   331 AIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEG---NDSSFLEFEMTGSTYEPI 392
            ||:|.||||||||..:|||||||||||.|.|:|::::....:..   .:|..:|.    |....:
pombe   309 AIIRRLPSVETLGSVNVICSDKTGTLTMNHMTVTKIYTCGMLAAFSLPESEHIEL----SVRRTV 369

  Fly   393 GEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEK----VGEATETALIVLAEKLN 453
            |                :::......:||:|.: :|:.....:.    .|...:.|||..:|:.
pombe   370 G----------------IEKALLAAALCNNSKV-HNKADSILDTTCPWAGFPVDVALIECSERF- 416

  Fly   454 SFSVNKSGL-DRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGA 517
                   || |.|          || :.:...:.||.:||.| |......:|::.     |:|||
pombe   417 -------GLKDPR----------ET-YSRISEVSFSSERKYM-SVAVQYNSSKMN-----FMKGA 457

  Fly   518 PEGVLERCTH-ARVGTTKVPLTSALKAKI------LALTGQYGTGRDTLRCLALAVADSPMKPDE 575
            .|.||..|.: :.....:..||:.:|..|      :|.:|        ||.:|:|...:..|
pombe   458 TEQVLSSCAYFSDQDGVQHELTAEMKENIQRNEFEMAASG--------LRIIAVASGINTNK--- 511

  Fly   576 MDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIG 640
                           |.|.|:.|:.||||.:|.:|:......|:|||:||||:..||.:|.|.:|
pombe   512 ---------------LVFHGLFGINDPPRPQVRESVQYLMTGGVRVIMITGDSVVTAISIARSLG 561

  Fly   641 --VFAEDEDTTGKSY--SGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMT 701
              :.:.||:.. ::|  :|.:.|||..:..:.||:|..:|:|..||||.||||.|||:.::.|||
pombe   562 MAIPSNDEEAI-RNYALTGAQLDDLDSSSLRDAVSRVVVFARTTPQHKMKIVEALQSLGDVVAMT 625

  Fly   702 GDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLI 765
            |||||||||||.|:|||||| .||.|||.||:|:|.||:|::|:||||||:.|:||:|.||.:.:
pombe   626 GDGVNDAPALKLADIGIAMGRQGTDVAKEAADMILTDDSFATILSAVEEGKGIFNNIKNFITFQL 690

  Fly   766 SSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLIS 830
            |:::..:..|.:::..|....|..:|:||:|::.||.||.:||....|.|:|.||||..:..:||
pombe   691 STSVAALSLIAISSVFGFQNPLNAMQILWINILMDGPPAQSLGVESVDEDVMMKPPRPRNAPIIS 755

  Fly   831 GWLFFRYMAIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPH 895
            ..|..|.:...|.:...|:                    :...:....|....:..
pombe   756 VQLLQRVLLSAFIIVTVTI--------------------VVFRVQMQDGNVTARDT--------- 791

  Fly   896 AMTMALSVLVTIEMLNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVT 960
              ||..:..|..:|.||:...||.:|:..:..:.|.....::..|.....:::|......:||..
pombe   792 --TMTFTCFVFFDMFNALACRSETKSVFKLGIFSNRMFNIAVGGSLIGQALVVYASPFQRIFQTE 854

  Fly   961 PLSAEEWITVMKFSIPVVLLDETLKFVARK 990
            .:..::.:.::..:..|:.:||..|:..|:
pombe   855 AIGLKDVLILLACTSSVLWVDEIRKWYRRR 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	328/1002 (33%)
pmr1	NP_595098.1	ATPase-IIA2_Ca	2..886	CDD:130585	329/1005 (33%)