Protein Alignment SERCA and atp2a2

DIOPT Version :10

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: XP_031748548.1
• Gene: atp2a2 / 100489059
• XenbaseID: XB-GENE-1012933
• Length: 1083
• Species: Xenopus tropicalis
• Alignment Length: 989
• Identity: 712/989 - (71%)
• Similarity: 840/989 - (84%)
• Gaps: 1/989 - (0%)

  Fly     1 MEDGHSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKIL 65
            ||:.|:||||:.|..|..:...||:|:|:|..::::|.||||.||||::|:||:|||:||||:||
 Frog     1 MENAHTKTVEEVLAHFNVNESTGLSLEQVKKQKERWGANELPAEEGKTLWELVIEQFEDLLVRIL 65

  Fly    66 LLAAIISFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVV 130
            ||||.||||||.|||.|||.||||||.||||||:|||:||||||||||:|||||||||||||||.
 Frog    66 LLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVY 130

  Fly   131 RQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIP 195
            |||:..:|:::|::|||||:|||:||||:|||||:|.|.|||||:|||||||||||||||||.:|
 Frog   131 RQDRKSVQRIKARDIVPGDIVEVAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVP 195

  Fly   196 DPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQL 260
            |||||||||||:||||||:|||||.|||:.||::|.|||||.||..||:.:||||||||||||||
 Frog   196 DPRAVNQDKKNMLFSGTNIAAGKAIGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQL 260

  Fly   261 SKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRR 325
            |||||:||:|||.|||||||||.||||||:|||||||||||||||||||||||||||||||||||
 Frog   261 SKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRR 325

  Fly   326 MAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEMTGSTYE 390
            ||||||||||||||||||||||||||||||||||||||.||||.|||||::....||.:|||||.
 Frog   326 MAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIVDKVEGDNCFLNEFNITGSTYA 390

  Fly   391 PIGEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSF 455
            |:|||..:.:.:|...||.|.||:|||.:||||::|:||.|..:|||||||||||..|.||:|.|
 Frog   391 PMGEVLKDDKLVKCHQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTCLVEKMNVF 455

  Fly   456 SVNKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEG 520
            ..:..||.|...|.||...|:...||||||||||||||||.||||.|.||.... |:||||||||
 Frog   456 DTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMS-KMFVKGAPEG 519

  Fly   521 VLERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFY 585
            :::||||.|||:.|||||:.:|.||:::..::|||||||||||||..|:|.:.::|:|.|||.|.
 Frog   520 LIDRCTHIRVGSIKVPLTAGIKQKIMSVIREWGTGRDTLRCLALATHDNPPRKEDMNLEDSTNFI 584

  Fly   586 QYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFAEDEDTTG 650
            .||.||||||.||||||||.||..|:..||.||||||:||||||.||.|||||:|:|.||||.:.
 Frog   585 NYETNLTFVGCVGMLDPPRTEVAASVKMCRQAGIRVIMITGDNKGTAVAICRRVGIFREDEDVSE 649

  Fly   651 KSYSGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAE 715
            ::::|||||:|||..|:.|...:|.|:||||.|||||||||||.:||:|||||||||||||||||
 Frog   650 RAFTGREFDELSPAAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAE 714

  Fly   716 IGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAA 780
            |||||||||||||:|:||||||||||:||:|||||||||||||||||||||||:||||.||||||
 Frog   715 IGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779

  Fly   781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVG 845
            ||.||||||||||||||||||||||||||||||||||.||||...|.||||||||||:|||.|||
 Frog   780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 844

  Fly   846 AATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEML 910
            |||||||||||:.:::||:::::||:|.|.|.....:|.||:|:||..|:.|||||||||||||.
 Frog   845 AATVGAAAWWFIAAEDGPRITFYQLSHFLQCREENPDFDGVECEIFESPYPMTMALSVLVTIEMC 909

  Fly   911 NAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSI 975
            ||:|||||||||:.||||.|:||:||:.||.:|||:||||:.|..:||:|||:..:|:.|:|.|:
 Frog   910 NALNSLSENQSLLRMPPWENVWLLGSICLSMSLHFLILYVEPLPLIFQITPLNLIQWLMVLKISL 974

  Fly   976 PVVLLDETLKFVAR 989
            ||:|||||||:|||
 Frog   975 PVILLDETLKYVAR 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	708/983 (72%)
atp2a2	XP_031748548.1	P-type_ATPase_SERCA	5..988	CDD:319778	708/983 (72%)