Protein Alignment SERCA and atp4a

DIOPT Version :9

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: XP_031762229.1
• Gene: atp4a / 100488221
• XenbaseID: XB-GENE-486104
• Length: 1031
• Species: Xenopus tropicalis
• Alignment Length: 1056
• Identity: 312/1056 - (29%)
• Similarity: 496/1056 - (46%)
• Gaps: 157/1056 - (14%)

  Fly     5 HSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKILLLAA 69
            |..|:|:....:.|:..:|:..........:.|||||...:|...:.....|....|..::.:||
 Frog    51 HEITIEELEQKYNTNVTKGMKATFAAEILIRDGPNELKPPKGTPEYVKFARQLAGGLQCLMWVAA 115

  Fly    70 IISFVLALFEEHEETFTAFVEPLVILLILIANAVV----GVWQERNAESAIEALKEYEPEMGKVV 130
            :|..:....|..:...|: .:.|.:.:.|||..||    |.:||..:.:.|.:.|...|:...|:
 Frog   116 VICLIAFGIECAQGDLTS-ADNLYLAITLIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVL 179

  Fly   131 RQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIK---HTD 192
            |..:.  .::.|.::|.|||||:..||::||||||  |.|...::|.|.|||||....:   :|.
 Frog   180 RDGEK--FQINANQLVVGDLVEIKGGDRVPADIRI--ITSQGCKVDNSSLTGESEPQTRSPEYTH 240

  Fly   193 AIPDPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFG 257
            ..|      .:.:||.|..|....|.|.||:|.||..|.||:|.:..|.....|||:
 Frog   241 ESP------LETRNIAFFSTMCLEGTATGVIINTGDRTIIGRIASLASGVGNEKTPI-------- 291

  Fly   258 EQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAV-------------ALAVAAIPE 309
                           ||.|.||.|...|.:...||.::....|             |:.||.:||
 Frog   292 ---------------AIEIEHFVDIIAGLAIFFGATFFVVAMVIGYPFLRAMVFFMAIVVAYVPE 341

  Fly   310 GLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEG 374
            ||.|.:|.||:|..:|:|:||.:|::|.:|||||.|||||||||||||.|:|:||.::..:::..
 Frog   342 GLLATVTVCLSLTAKRLARKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNQIHS 406

  Fly   375 NDSSFLEFEMTGSTYEPIGEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEK--- 436
            .|::   .:.:|.:::...              ||.:.||.:..:||.:.....:......|
 Frog   407 ADTT---EDQSGQSFDQTS--------------DTWRALSKVTSLCNRACFKSGQDGVPIPKRIV 454

  Fly   437 VGEATETALIVLAEKLNSFSVNKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRK---SMSSYC 498
            :|:|:||||:..:|                ..:....|...::||...|.|:...|   |:....
 Frog   455 IGDASETALLKFSE----------------LTVGNVMEYRDRFKKATELPFNSTNKFQLSIHELQ 503

  Fly   499 TPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALTGQY----GTGRDTL 559
            .||....|     |.:|||||.:||||:...:...::||....|.   |....|    |.|...|
 Frog   504 DPLDLRYL-----LVMKGAPERILERCSTIMIKGQELPLDEQWKE---AFQTAYMDLGGLGERVL 560

  Fly   560 RCLALAVADSPMKPDEMDLGDSTKFYQYEVN-----LTFVGVVGMLDPPRKEVFDSIVRCRAAGI 619
            ....|.:       :|.:......|...|:|     |.|.|::.|:||||..|.|::::||.|||
 Frog   561 GFCHLYL-------NEKEYPRGFSFDTEEMNFPTSGLCFAGLISMIDPPRATVPDAVMKCRTAGI 618

  Fly   620 RVIVITGDNKATAEAICRRIGVFAEDEDTT--------------------GKSYSGREFDDLSPT 664
            |||::|||:..||:||...:|:.:|..:|.                    ....:|.:..|::..
 Frog   619 RVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRIPVEQVNKRDARACVINGGQLKDMTSE 683

  Fly   665 EQKAAVA--RSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMG-SGTAV 726
            |...|:.  ...:|:|..||.|..|||..|.:..|.|:|||||||:||||||:||:||| :|:..
 Frog   684 ELVEALKLHPEMVFARTSPQQKLIIVESCQKLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDA 748

  Fly   727 AKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVS--IFLTAALGLPEALIP 789
            ||:||:|:|.||||:|||:.||:||.|::|:|:.|.|.::.||.|:..  |::||::.||...|.
 Frog   749 AKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELAPYLIYITASVPLPLGCIT 813

  Fly   790 VQLLWVNLVTDGLPATALGFNPPDLDIMEKPPR--KADEGLISGWLFFRYMAIGF------YVGA 846
            :  |::.|.||..|:.:|.:...:.|||...||  :.|..:......:.|..:|.      :|..
 Frog   814 I--LFIELCTDIFPSVSLAYERAESDIMHLKPRNPRRDRLVNEALAVYSYFQVGIIQSFAGFVDY 876

  Fly   847 ATVGAAAWWFVFSDEGPKLSYWQLTHHLSCL--GGGDEFKGVDCKIFSDPHAMTMALSVLVTIEM 909
            .||.|...||.....|.: |:|: ..||..|  ..|.::. ...:::...:..|:....:...::
 Frog   877 FTVMAQEGWFPAYVLGLR-SHWE-NQHLQDLEDSYGQQWT-FSQRLYQQYNCYTVFFISIEVCQI 938

  Fly   910 LNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFS 974
            .:.:...:...|:.....:.|..|:.::.....|...:.|...:..||...|:..:.|:..:.|.
 Frog   939 ADVLIRKTRRLSVFQQGFFRNKVLVIAIVFQLCLGNFLCYCPGMPNVFNFMPIRFQWWLVPVPFG 1003

  Fly   975 IPVVLLDETLKFVARK 990
            |.:.:.||..|...|:
 Frog  1004 ILIFVYDEIRKLGVRR 1019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	311/1053 (30%)
atp4a	XP_031762229.1	ATPase-IIC_X-K	39..1031	CDD:273445	312/1056 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920