Protein Alignment arhgap28 and cv-c

DIOPT Version :9

• Sequence 1: NP_001007436.1
• Gene: arhgap28 / 492794
• ZFINID: ZDB-GENE-041114-147
• Length: 638
• Species: Danio rerio
• Sequence 2: NP_001097786.1
• Gene: cv-c / 41749
• FlyBaseID: FBgn0285955
• Length: 2351
• Species: Drosophila melanogaster
• Alignment Length: 830
• Identity: 169/830 - (20%)
• Similarity: 279/830 - (33%)
• Gaps: 304/830 - (36%)

Zfish     3 VQDCGGVILTAFHSFRTHADDEQ----------KHTAADNRKAQ--HQPIVSMSVCG------PG 49
            |:.|..:....|..:....:|.|          .||..:|.:.|  ::.:..::.|.      ..
  Fly  1382 VEACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMRLDQSH 1446

Zfish    50 APASPEQCVSRD----SMEDYWSEVKNIQEDTHTHQQ--------------EPAEQASTDEA--E 94
            .|.:|:|....|    ::.::|:...:|:..:...:.              |..|.:|.:.:  .
  Fly  1447 KPQTPQQKEESDDENFALSEHWTFQPHIRRWSRIGEMGLELPPPGLLSLNVEKTESSSKESSPDR 1511

Zfish    95 LEEAWLQDAGLTTLITGAQ------------GDGPTEALL----STLTHSQAAMVKKRLDNYTHT 143
            .||   ..||:|.:..|..            |:|.....|    |.....||..:.:|:::....
  Fly  1512 FEE---DGAGITLVTPGCSKAGGIPNDGSSLGEGSDSGRLRRSGSERIKDQAKALLRRVESIKSR 1573

Zfish   144 LRKK-NRQ------PT-------------RHVRDVFSTPEPASELTSPVSPNGEISPKPP-QSNP 187
            .||: ||:      ||             |....|:||| |:....||:    ...||.| ..|.
  Fly  1574 RRKRQNRENVVISGPTVLDLSQFGQRSSLRKPDAVYSTP-PSPSALSPM----HTFPKAPFFGND 1633

Zfish   188 PKAPPACPDFTS---ADSKGSSSTLRTIILS----FSTPYSE-------------------GTRG 226
            .|.|....:|.|   :..|.:.:|.|::..|    ||:|.|:                   .|.|
  Fly  1634 LKVPSHSDNFLSPNRSSPKRTPTTPRSMRTSPLHFFSSPMSQLKEGKSDDSSSYYSDSQESSTGG 1698

Zfish   227 QQKLREMQECRKIRK-----------------EDRELLCFQVVKPRQGTTRV----------MDL 264
            :..||:..:.|:..:                 :.|:||   :......||.|          ::|
  Fly  1699 KLSLRKPSKARRFLQRTGKVDDIGAHSDSECHQGRKLL---IKDANSNTTEVKVKKLTRGGSLNL 1760

Zfish   265 SSDDMRKIGYIS------------------LIELTTFYG----------NLGIELRRNRV----- 296
            ..|..::.|:.|                  ....||..|          :..:|.|.|.:
  Fly  1761 GKDPKKRDGFRSSSFRSRSTSRKEAKNDEDTAGATTNGGSKRQPVVRWHSFQMEERPNMIFRKCF 1825

Zfish   297 -------------MPVKA----------------------------------------------- 301
                         ||..|
  Fly  1826 SKKIEPLQEDAGGMPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFIKKIKMPD 1890

Zfish   302 -RDTGIFGVPLLTLLQNDRKIYPGSRIPLFFKKLLAKLEQTGLQTEGILRVPGSAVRVKQLRQEL 365
             :|..:||||||.:||..     |..:||..:.....|:...|...||.|..|...|:.:||:::
  Fly  1891 YKDKKVFGVPLLMILQRS-----GQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQI 1950

Zfish   366 DLHFYD------DRFDWDQVHQNDAAALLKMFIRELPYPLLTKLNMPAFTALQRISSPKYQIQAL 424
            ::  .|      |.||..|.:  |.|.:||.:.||||..|||......|.|:.:....:.::.|:
  Fly  1951 EV--TDSTAECMDVFDLQQAY--DVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAV 2011

Zfish   425 HLLIMILPEPNRDTLKALLEFLRKVVACEEKNRMNVWNVSMIVAPNLF---------------TY 474
            ...:::||:.||:.|..|||||..|.|..::|:|...|:.:.:|.::|               ..
  Fly  2012 QCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRR 2076

Zfish   475 IGKNAKQEEVKSALAAAQIVCTLISHQDLLWTVPCFLINQVRKMNDAAMAKKSLSS----ERSK- 534
            .||.:...::|. ||.|:     .||:.|     .|:|...:::..||..|.|..:    |.||
  Fly  2077 KGKGSGMPDMKE-LAEAK-----ASHECL-----SFMIEHYKQIYTAAKEKLSKCNFSYMEESKP 2130

Zfish   535 ---------------RGLL----------SRWKDRERSEVKDLRDGVIRV 559
                           ||.|          .|.|.|....:..|.|..:.:
  Fly  2131 LPLEALGEGMQFHNWRGYLYECTSATIKEGREKTRGWFSINSLNDSSVDI 2180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
arhgap28	NP_001007436.1	RhoGAP_ARHGAP18	306..516	CDD:239856	67/230 (29%)
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937	10/58 (17%)
		RhoGAP_DLC1	1893..2116	CDD:239840	70/242 (29%)
		SRPBCC	2148..2343	CDD:301327	6/33 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910