DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-87B and PPT1

DIOPT Version :9

Sequence 1:	NP_524937.1	Gene:	Pp1-87B / 49260	FlyBaseID:	FBgn0004103	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	252	Identity:	99/252 - (39%)
Similarity:	146/252 - (57%)	Gaps:	15/252 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 IFLSQPILLELE------APLKICGDIHGQYYDLLRLF-EYGGFPPESNYLFLGDYVDRGKQSLE 100
            :|..:|.::|||      ..:.:|||.|||:||:|.|| ::|...|:..|||.||:||||..|.|
Yeast   224 LFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCE 288

  Fly   101 TICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDE 165
            ...|....||.:..||||.|||||..::|:||||.||||.:||.:::..|...|..||:|.:::.
Yeast   289 VALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFAQSFESLPLATLINN 353

  Fly   166 KIFCCHGGLSPD----LTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFG 226
            .....||||..|    |:..:.|.|..:|   |..|...:|||:|| ::..|.|.:.||:...||
Yeast   354 DYLVMHGGLPSDPSATLSDFKNIDRFAQP---PRDGAFMELLWADP-QEANGMGPSQRGLGHAFG 414

  Fly   227 AEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSV 283
            .::..:||:.::...|.|:|::...|.:|..|..|:|:|||||||....|.|.::.|
Yeast   415 PDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVIHV 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	99/252 (39%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	99/252 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810