DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-87B and PPH3

DIOPT Version :9

Sequence 1:	NP_524937.1	Gene:	Pp1-87B / 49260	FlyBaseID:	FBgn0004103	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_010360.1	Gene:	PPH3 / 851647	SGDID:	S000002482	Length:	308	Species:	Saccharomyces cerevisiae

Alignment Length:	294	Identity:	131/294 - (44%)
Similarity:	192/294 - (65%)	Gaps:	12/294 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VMNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYY 68
            :|::|.||:.|      |.||::  .|..:..|||.|:|:.:::..:.:::.|:.||||||||.:
Yeast     1 MMDLDKIIASL------RDGKHI--PEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLH 57

  Fly    69 DLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYG 133
            |||.|||..|...::.|:||||:||||..|||:..|||.||::|.:...|:|||||...|.::||
Yeast    58 DLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYG 122

  Fly   134 FYDECKRRY-SIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQG 197
            ||||..|:| :..:|:...:.|:.|.:.||::..|||.|||||||:|::::||.|.|..:||.:|
Yeast   123 FYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEG 187

  Fly   198 LLCDLLWSDP-DKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRML 261
            .:|||||||| |.||  |..:.||..|.||...|.:||:|:..:||.||||:|.:||:......|
Yeast   188 AMCDLLWSDPEDVDT--WSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGL 250

  Fly   262 VTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILK 295
            ||::||||||....|..|::.:||.|...:.|.:
Yeast   251 VTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFE 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	130/292 (45%)
PPH3	NP_010360.1	MPP_PP2A_PP4_PP6	3..286	CDD:277360	130/292 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820