DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pp1-87B and Ppef1

DIOPT Version :9

Sequence 1:	NP_524937.1	Gene:	Pp1-87B / 49260	FlyBaseID:	FBgn0004103	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_011246120.1	Gene:	Ppef1 / 237178	MGIID:	1097157	Length:	676	Species:	Mus musculus

Alignment Length:	319	Identity:	94/319 - (29%)
Similarity:	147/319 - (46%)	Gaps:	57/319 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 KSREIFLSQPILLELEA-PLK---ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQS 98
            ::|::....|....::. |.|   ||||:||:..||:.:|...|.|.|:| |:|.||:||||..|
Mouse   174 EARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNS 238

  Fly    99 LETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSI---KLWKTFTDCFNCLPVA 160
            :|.:.:||...:.|..:..|.|||||...:|..|||..|..::|.:   |:.:...:.:..||:.
Mouse   239 MEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIG 303

  Fly   161 AIVDEKIFCCHGGL--SPDLTSMEQIR--------------------------------RIMRPT 191
            .|:|.:|...|||:  |.||.::.|::                                |.:.|.
Mouse   304 TIIDNEILVIHGGISESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPD 368

  Fly   192 DVPDQGL-------LCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVV 249
            ..|.:.|       :.|:|||||......:....||....||.:|.:|.|.|::..::.|:|:..
Mouse   369 KTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECK 433

  Fly   250 EDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSF--------QILKPADKR 300
            .||||......::|:|||.||..|..|.||.:.:....|..|        ..|.|..:|
Mouse   434 PDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQYQVTSTSCLNPLHQR 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	92/313 (29%)
Ppef1	XP_011246120.1	MPP_RdgC	144..479	CDD:277364	91/304 (30%)
		PTZ00183	518..660	CDD:185503
		EF-hand_7	595..663	CDD:372618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810