DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-87B and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_524937.1	Gene:	Pp1-87B / 49260	FlyBaseID:	FBgn0004103	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_114074.1	Gene:	Ppp1ca / 19045	MGIID:	103016	Length:	330	Species:	Mus musculus

Alignment Length:	297	Identity:	277/297 - (93%)
Similarity:	287/297 - (96%)	Gaps:	0/297 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYD 69
            :|:||||.|||||:|:||||||||:|.||||||||||||||||||||||||||||||||||||||
Mouse     7 LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYD 71

  Fly    70 LLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGF 134
            |||||||||||||||||||||||||||||||||||||||||:|.|||||||||||||||||||||
Mouse    72 LLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGF 136

  Fly   135 YDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLL 199
            ||||||||:|||||||||||||||:|||||||||||||||||||.||||||||||||||||||||
Mouse   137 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLL 201

  Fly   200 CDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTL 264
            |||||||||||..||||||||||||||||||||||.||:.||||||||||||||||||||.||||
Mouse   202 CDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTL 266

  Fly   265 FSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRK 301
            ||||||||||||||||||||:||||||||||||||.|
Mouse   267 FSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNK 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	271/289 (94%)
Ppp1ca	NP_114074.1	PTZ00480	6..308	CDD:185658	277/297 (93%)
		MPP_PP1_PPKL	8..298	CDD:277359	271/289 (94%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837158
Domainoid	1	1.000	395	1.000	Domainoid score	I758
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	602	1.000	Inparanoid score	I936
Isobase	1	0.950	-	0	Normalized mean entropy	S19
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		mtm8882
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R952
SonicParanoid	1	1.000	-	-		X337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750