DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-87B and pph-5

DIOPT Version :9

Sequence 1:	NP_524937.1	Gene:	Pp1-87B / 49260	FlyBaseID:	FBgn0004103	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001367002.1	Gene:	pph-5 / 180263	WormBaseID:	WBGene00012665	Length:	496	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	104/244 - (42%)
Similarity:	156/244 - (63%)	Gaps:	7/244 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SQPILLELEAP----LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLL 105
            |.|.::|:..|    ..||||:|||:|||..:||..|:|.|:| |||.||:||||..|:|||..:
Worm   221 SLPTMVEITVPTGKKFTICGDVHGQFYDLCNIFEINGYPSETNPYLFNGDFVDRGSFSVETIFTM 285

  Fly   106 LAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCC 170
            :.:|:.|..:||:.|||||...:|::|||..|.|.:|:.::...||:.|..||:..:::||||.|
Worm   286 IGFKLLYPNHFFMSRGNHESDVMNKMYGFEGEVKAKYTQQMCDMFTETFCWLPLCHLINEKIFVC 350

  Fly   171 HGGL-SPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFL 234
            |||| ..|..::|.||:..|....||:|::|||||||| :...|...:.|||...||.:|.:|:.
Worm   351 HGGLFKEDGVTLEDIRKTDRNRQPPDEGIMCDLLWSDP-QPINGRSPSKRGVGCQFGPDVTSKWC 414

  Fly   235 QKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSV 283
            :.:..:.:.|:|:|..:|||........|:|||||||.:.:|.||.:::
Worm   415 ETNGIEYVVRSHEVKPEGYEMHHNGQCFTVFSAPNYCDQMNNKGAFITI 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	104/244 (43%)
pph-5	NP_001367002.1	PLN03088	29..>139	CDD:215568
		TPR repeat	33..57	CDD:276809
		TPR repeat	62..91	CDD:276809
		TPR repeat	96..124	CDD:276809
		MPP_PP5_C	176..490	CDD:277362	104/244 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910