DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-87B and pef-1

DIOPT Version :9

Sequence 1:	NP_524937.1	Gene:	Pp1-87B / 49260	FlyBaseID:	FBgn0004103	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_741091.1	Gene:	pef-1 / 175257	WormBaseID:	WBGene00003969	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	270	Identity:	95/270 - (35%)
Similarity:	145/270 - (53%)	Gaps:	29/270 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 KSREIFLSQP----ILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQS 98
            ::|:||.:.|    |...:...:.||||:||::.||..:....|:|...| |:|.||:||||.||
Worm   229 EARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQS 293

  Fly    99 LETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRY---SIKLWKTFTDCFNCLPVA 160
            :|.:|:|.|..|....:.:|.|||||...:|..|||..|...:|   |..:.:...|.|:.||:|
Worm   294 IEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIA 358

  Fly   161 AIVDEKIFCCHGGLS--PDLTSMEQIRR-----IMRP--------------TDVPDQGLLCDLLW 204
            .|:|..||..|||:|  .:::.:::|.|     ::||              .:|.:...:.|::|
Worm   359 TIIDRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMW 423

  Fly   205 SDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPN 269
            |||.::...|....||....|||::.|.||:||.|.|:.|:|:...:||||......:|:|||.|
Worm   424 SDPKQNKGCWPNVFRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASN 488

  Fly   270 YCGEFDNAGA 279
            |.....|.||
Worm   489 YYETGSNRGA 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	95/270 (35%)
pef-1	NP_741091.1	MPP_RdgC	199..515	CDD:277364	95/270 (35%)
		PP2Ac	218..514	CDD:197547	95/270 (35%)
		EFh	634..699	CDD:238008
		EF-hand_7	634..698	CDD:290234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910