Protein Alignment rec and MCM7

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_009761.4
• Gene: MCM7 / 852501
• SGDID: S000000406
• Length: 845
• Species: Saccharomyces cerevisiae
• Alignment Length: 848
• Identity: 190/848 - (22%)
• Similarity: 343/848 - (40%)
• Gaps: 206/848 - (24%)

  Fly   117 LYFLREKYEEGNELATRIMAVEAYYQRNPHTFDFVMIR--DRGF-FPLCAAGIKSDAQLKEVWPS 178
            |.:..||:.:|.:....:.|:    |:|.:.|..:..|  |... .|......|.|.
Yeast    86 LQYQNEKFLQGTQADDLVSAI----QQNANHFTELFCRAIDNNMPLPTKEIDYKDDV-------- 138

  Fly   179 LSEDIREHPLRTLGTLSLAMHTVVVNHQLD--------CNDSTTAMVSTPEQYVLPTPRVRKIYA 235
            |...:.:..||....||...:.:...:.:|        .||:...:|. .|..:.|....|:.:.
Yeast   139 LDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDALREVVE-DETELFPPNLTRRYFL 202

  Fly   236 RPDDFVPVE-----------------SIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSR 283
            .   |.|:.                 |:..|....:..|.::||.::.|.:...::...|:.|.:
Yeast   203 Y---FKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQ 264

  Fly   284 CQMEIAMRQRG-TFQPRPYQCKRSECVARDE----FVPLRSSPYTRLSIRQIIRVEESS--LNLV 341
            |..|:...... ||.|.. :|...||.....    |:..|:|   :.|..|..:::|.|  :.:.
Yeast   265 CGYEVFQEVNSRTFTPLS-ECTSEECSQNQTKGQLFMSTRAS---KFSAFQECKIQELSQQVPVG 325

  Fly   342 HDFETSMPAEMDVELRHDLVDAVRVGQEVVVTGI--------LKLQELGDDTTTGDTSNQMQPYL 398
            |     :|..:::.:...||.::..|..|.||||        .|..:.|..|.|         ||
Yeast   326 H-----IPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTET---------YL 376

  Fly   399 KAVSIRD------ASSIKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLL 457
            :|..:|.      :.|:..:..||.:|.|    ...:.:..|.:|||||:||:...|.|.||.|:
Yeast   377 EAQFVRQHKKKFASFSLTSDVEERVMELI----TSGDVYNRLAKSIAPEIYGNLDVKKALLLLLV 437

  Fly   458 G------GKGAETEA-INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFA-- 513
            |      |.|.:... |||.|:||||:.|:::|::..:|:.||.:.:||    .:..:|:|.|
Yeast   438 GGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGK----GSSGVGLTAAVM 498

  Fly   514 ---GRNKRVLQAGSLMMASGGGHCTLDDVDKL-ASKQAVLLQCLQSEEVNLPLAGAFASFPAQPS 574
               ..::.:|:.|:|::|. .|.|.:|:.||: .|.:..:.:.::.:.:::..||...:..|:.|
Yeast   499 KDPVTDEMILEGGALVLAD-NGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTS 562

  Fly   575 VIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPS-ERDMSLTAHVRALHAGARKRA 638
            ::|.|||..|:|:.....|.|||:..:||..|.:::::||.|| :.|..|..||..:|
Yeast   563 ILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVH------- 620

  Fly   639 RIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLL 703
                                                                  :..::.|||..
Yeast   621 ------------------------------------------------------MHNKQPDLDFT 631

  Fly   704 P--PILIKKFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSSQIGAGQ-----LLAII 761
            |  |..::::::||:.: .||::|..::.|::.::.|:.....:.|  |:...||     ||.||
Yeast   632 PVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSKREMD--SKFSFGQATPRTLLGII 693

  Fly   762 HLSQARARLDLSHVVSPQHVRDVIALL---TESITQTSLKEGSSRQGTRGGGGAGGGAGKSAQLR 823
            .||||.|:|.|:.:|....|.:.:.|:   .||:.|.:.|.......|                .
Yeast   694 RLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPT----------------T 742

  Fly   824 NFLELTKRRSAALGRRIFEFDELKEIGTRAGILTGFSQL------VEMANLGGYLLMKGANMYEV 882
            ....:.|:.....|:....::.:    .:...|.||:.|      .|.:.|..:.|:...|..:.
Yeast   743 KIFTIIKKMLQETGKNTLSYENI----VKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEGNTLKF 803

  Fly   883 VPD 885
            |.|
Yeast   804 VDD 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	163/691 (24%)
		MCM8	433..791	CDD:350665	100/381 (26%)
		MCM8_WHD	819..883	CDD:439328	10/69 (14%)
MCM7	NP_009761.4	MCM_N	59..138	CDD:464206	12/55 (22%)
		MCM	223..724	CDD:214631	146/591 (25%)