back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rec and MCM3

DIOPT Version :9

Sequence 1:	NP_001262615.1	Gene:	rec / 49241	FlyBaseID:	FBgn0003227	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_199440.1	Gene:	MCM3 / 834670	AraportID:	AT5G46280	Length:	776	Species:	Arabidopsis thaliana

Alignment Length:	682	Identity:	164/682 - (24%)
Similarity:	278/682 - (40%)	Gaps:	147/682 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 HTVVVN-----HQLDCNDSTTAMVSTPEQYV-----LPTPRVRKI---YARPDDFVPVESIEGIS 250
            |.:::|     |..  .:..:.::..|.:|:     ..|...|.|   |.:..:.|.| ..||..
plant    36 HRLIINISDIHHHF--REVASRILKNPNEYMQSFCDAATEATRAIDPKYLKEGELVLV-GFEGYF 97

  Fly   251 HSRVDT-----------LFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMR-----QRGTFQPR 299
            .|||.|           :..:.|.|:              :||..:.::...     ..|.|..|
plant    98 VSRVVTPRELLSDFIGSMVCVEGIVT--------------KCSLVRPKVVKSVHFCPSTGEFTNR 148

  Fly   300 PYQCKRSEC--------VARDEFVPLRSSPY--TRLSIRQIIRVEESSLNLVHDFETSMPAEMDV 354
            .|:...|..        ..||:...|..:.|  .:....|.:.::|...|..   ...:|..:||
plant   149 DYRDITSHAGLPTGSVYPTRDDKGNLLVTEYGLCKYKDHQTLSIQEVPENAA---PGQLPRSVDV 210

  Fly   355 ELRHDLVDAVRVGQEVVVTGILKLQELGDDTTTGDTSNQMQPYLKAVSI-RDASSIKRE-----F 413
            ....||||:.:.|..|.|.||.|       ...|.:...:....:.:.| .:.:.:.:|     :
plant   211 IAEDDLVDSCKPGDRVSVFGIYK-------ALPGKSKGSVNGVFRTILIANNIALLNKEANAPIY 268

  Fly   414 SERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGG------KGAETEA-INVLL 471
            :::||:.|..|....::|.||.:|:||.:|||...|.|.:|.:|||      .|..... ||:::
plant   269 TKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMM 333

  Fly   472 VGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFA-----GRNKRVLQAGSLMMASGG 531
            ||||.:.|:::|::...||......:| ||:..   :|:|.|     ...:|.|:||::::|..|
plant   334 VGDPSVAKSQLLRAIMNIAPLAISTTG-RGSSG---VGLTAAVTSDQETGERRLEAGAMVLADKG 394

  Fly   532 GHCTLDDVDKLASKQAVLL-QCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQN 595
            ..| :|:.||:..:..|.: :.::.:.|.:..||..||..|:.||:|.|||..|.||......:|
plant   395 IVC-IDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKN 458

  Fly   596 INISPSLLREFHLVYILLDK-PSERDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSL 659
            |.:..|||..|.|::|:||: .:..|..::.||..:|.....|..
plant   459 IGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYKNDRGE-------------------- 503

  Fly   660 NVPAAGKDDDTIKTEDDN-DSIMQQDYDL------------DKRLEVLPEEGDLDLLPPILIKKF 711
                ||.|.......:|| :|.|...|:.            ||.|.:.            .:||:
plant   504 ----AGPDGSLPYAREDNAESEMFVKYNQTLHGKKKRGQTHDKTLTIK------------FLKKY 552

  Fly   712 LSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSS----QIGAGQLLAIIHLSQARARLDL 772
            :.||:..:.|.|.::||..:...:.:|:   |...|..:    .|.|..|..||.|:.|.|::.|
plant   553 IHYAKHRITPKLTDEASERIAEAYADLR---NAGSDTKTGGTLPITARTLETIIRLATAHAKMKL 614

  Fly   773 SHVVSPQHVRDVIALLTESITQTSLKEGSSRQ 804
            |..|:.......:.|:..:|....|.|...|:
plant   615 SSEVTKADAEAALKLMNFAIYHQELTEMDDRE 646

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.