Protein Alignment rec and mcm6

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_001076318.1
• Gene: mcm6 / 566409
• ZFINID: ZDB-GENE-030909-6
• Length: 830
• Species: Danio rerio
• Alignment Length: 738
• Identity: 169/738 - (22%)
• Similarity: 295/738 - (39%)
• Gaps: 193/738 - (26%)

  Fly   228 PRVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQ 292
            |..::.|....|......|..::..:|.:|..|.|.|.........|....|.|..||..|...:
Zfish   103 PTSKEFYVAFQDLPTRHKIRELTTVKVGSLVRISGQVVRTHPVHPELVSGTFLCLDCQGVIKDVE 167

  Fly   293 RGTFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDVELR 357
            :.....:|..|:...|..|..|  |..:..::....|.:|::|:...|...   |:|..|:|.||
Zfish   168 QQFKYTQPSICRNPVCNNRRRF--LLDTNKSKFIDFQKLRIQETQAELPRG---SIPRSMEVILR 227

  Fly   358 HDLVDAVRVGQE-------VVVTGILKLQELGDDTTTGDTSNQMQPY-------LKAVSIRD--- 405
            .:.|::.:.|.:       :||..|.:|...|....|...:..:|.|       |||:.:|:
Zfish   228 AEAVESAQAGDKCDFIGSLIVVPDISQLATPGVRAETSSRTAGVQGYENEGLRGLKALGVRELSY 292

  Fly   406 ---------------------------ASSIKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVY 443
                                       |.|||::.|.::.|.:..::.:.|.:..|..|:.|.::
Zfish   293 KLAFLACHVAPTNPRFGGKEIRDEEQTAESIKKQMSVQEWEKVFEMSQDKNLYHNLCTSLFPTIH 357

  Fly   444 GHELPKAACLLSLLGG------KGAETEA-INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRG 501
            |::..|...||.|.||      :|..... |||.:||||...|::.|:...:...|..:.|||
Zfish   358 GNDEVKRGILLMLFGGVPKTTMEGTSLRGDINVCVVGDPSTAKSQFLKHVEEFCPRAVYTSGK-- 420

  Fly   502 AQSAQQLGVTFA-----GRNKRVLQAGSLMMASGGGHCTLDDVDKLASK-QAVLLQCLQSEEVNL 560
            |.||  .|:|.|     ..::.|::||:||:|. .|.|.:|:.||:.:: |..:.:.::.:.:::
Zfish   421 ASSA--AGLTAAVVRDEESHEFVIEAGALMLAD-NGVCCIDEFDKMETRDQVAIHEAMEQQTISI 482

  Fly   561 PLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSE-RDMSLT 624
            ..||..|:..|:.|::|.|||..|:||..:.|.||:|::..::..|.|.:||:|..:| .|.::.
Zfish   483 TKAGVKATLNARTSILAAANPVSGRYDRSKSLKQNVNLTAPIMSRFDLFFILVDDCNEVTDYAIA 547

  Fly   625 AHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDK 689
            ..:..||:                                       :.|:..|.:    |.||:
Zfish   548 RRIVDLHS---------------------------------------RIENSVDRV----YSLDE 569

  Fly   690 RLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSS---- 750
                              |:::|.:||| ..|.:::::...::..:..|:     ..|.|.
Zfish   570 ------------------IRRYLLFARQ-FKPKISKESEEFIVEQYKRLR-----QRDGSGVTKS 610

  Fly   751 --QIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESI-------------TQTSLKEG 800
              :|...||.::|.||::.||:.....|.|:||::...||.:||             .:.:::|.
Zfish   611 AWRITVRQLESLIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEEAMEEE 675

  Fly   801 SSRQ--------GTRG----------------GGGAGGGAGKSA---------QLRNFLELTKRR 832
            ...|        |..|                |.|..|...|.:         ::.|.|.|..||
Zfish   676 EDNQMNGHDVPNGVNGAVNGEVNGHEHTNGINGHGVNGETAKPSLRLSFAEYKRISNLLVLHLRR 740

  Fly   833 S------AALGRRIFEFDELKEI 849
            :      |||.:.......||||
Zfish   741 AEEDEDEAALKKSEVVNWYLKEI 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	149/647 (23%)
		MCM8	433..791	CDD:350665	95/377 (25%)
		MCM8_WHD	819..883	CDD:439328	12/46 (26%)
mcm6	NP_001076318.1	MCM_N	25..114	CDD:464206	2/10 (20%)
		MCM	117..655	CDD:475121	145/614 (24%)
		MCM6_C	718..826	CDD:465688	12/46 (26%)