Protein Alignment rec and mcm6l

DIOPT Version :9

• Sequence 1: NP_001262615.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_001020704.1
• Gene: mcm6l / 564982
• ZFINID: ZDB-GENE-050913-141
• Length: 824
• Species: Danio rerio
• Alignment Length: 844
• Identity: 195/844 - (23%)
• Similarity: 326/844 - (38%)
• Gaps: 225/844 - (26%)

  Fly   168 SDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTVV-VNHQLDCNDSTTAMVSTPEQY--VLP--- 226
            ||||         |.||  |.|  .||:::...:. .|.||    :||..    |:|  |.|
Zfish    42 SDAQ---------ELIR--PER--NTLTVSFSNIEHYNQQL----ATTIQ----EEYYRVYPFLC 85

  Fly   227 ------------TPRVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAF 279
                        .|..::.|....:|...:.|..:|..|:.||..|.|.|.........|....|
Zfish    86 RAVRHFARDHGNIPPSKEFYVAFSEFPSRQKIRELSTVRIGTLLRISGQVVRTHPVHPELVSGTF 150

  Fly   280 RCSRCQMEIAMRQRGTFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDF 344
            .|..||..|...::.....:|..||...|..|..|  :..:..:|....|..|::|:...|...
Zfish   151 LCLDCQSVIKDVEQQFKYTQPTICKNPVCANRRRF--MLDTNKSRFVDFQKGRIQETQAELPRG- 212

  Fly   345 ETSMPAEMDVELRHDLVDAVRVGQEVVVTGIL----KLQELGDDTTTGDTSNQMQ---------- 395
              |:|..::|.||.:.|:..:.|.....||.|    .:..:....|..:||:::.
Zfish   213 --SIPRSVEVILRAEAVETAQAGDRCDFTGTLVVVPDVSAMALAGTRAETSSRVTGKEGFETDGI 275

  Fly   396 PYLKAVSIRD------------------------------ASSIKREFSERDLEAIVMINAEPNS 430
            ..|||:.:|:                              |.|:|.:.:..:.|.:..::.:.|.
Zfish   276 QGLKALGVRELSYRLAFLANYVAPTNPRFGGKELRQEDQTAESVKNQMTVLEWEKVFEMSQDKNL 340

  Fly   431 FKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETEA-------INVLLVGDPGIGKTKILQSCAQ 488
            :..|..|:.|.::|::..|...||.|.||....|..       |||.:||||...|::.|:....
Zfish   341 YHNLCTSLFPTIHGNDEIKRGILLMLFGGVAKTTMEGTSLRGDINVCIVGDPSTSKSQFLKHVED 405

  Fly   489 IAERGAHVSGKRGAQSAQQLGVTFA-----GRNKRVLQAGSLMMASGGGHCTLDDVDKLASK-QA 547
            .|.|..:.|||  |.||  .|:|.|     ..::.|::||:||:|. .|.|.:|:.||:..| |.
Zfish   406 FAPRAVYTSGK--ASSA--AGLTAAVVKDEESHEFVIEAGALMLAD-NGVCCIDEFDKMDLKDQV 465

  Fly   548 VLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYIL 612
            .:.:.::.:.:::..||..|:..|:.|::|.|||..|:|:..:.|.||:|:|..::..|.|.:||
Zfish   466 AIHEAMEQQTISITKAGVKATLNARTSILAAANPIDGRYNRAKSLKQNVNMSAPIMSRFDLFFIL 530

  Fly   613 LDKPSE-RDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDD 676
            :|:.:| .|.::...:..|||                                           .
Zfish   531 VDECNEVTDYAIARRIVDLHA-------------------------------------------R 552

  Fly   677 NDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFLELKGS 741
            |...:::.|..|:                  |::::.:||| ..|.:..:|...|:..:..|:..
Zfish   553 NVESVERVYSTDE------------------IQRYILFARQ-FQPKITVEAQEFVVDQYKRLRQR 598

  Fly   742 CNLDEDVSS-QIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESITQTSLKE------ 799
            .......|: :|...||.:::.||:..|||..|..|.|:||::...||.:||.:....:
Zfish   599 DGGGTTKSAWRITVRQLESMLRLSEGMARLYCSDEVQPKHVKEAFRLLNKSIIRVDSPDINFDQE 663

  Fly   800 -------------GSSRQGTRGGGGAG----------------GGAGKSAQLRNFLELTKRRSAA 835
                         |...:|..||...|                ..|.|.|...:|.|. ||.|..
Zfish   664 HDEDNINDQNELFGKETEGQNGGDVNGHAVEDMETDQTEKPEKPAAAKPALRMSFAEY-KRVSNL 727

  Fly   836 L---GRRIFEFDE-------------LKEIGTRAGILTGFSQLVEMANLGGYLLMKGANMYEVV 883
            |   .:::.:.||             ||||.:.   :...::||...||...:|.:..|...::
Zfish   728 LVLHMQKMEQLDEDSSLKKSELINWYLKEIESE---IDSEAELVAKKNLIERVLYRLINFDHII 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_001262615.1	RNR_PFL	<117..200	CDD:299130	11/31 (35%)
		MCM	243..792	CDD:214631	144/607 (24%)
		P-loop_NTPase	468..606	CDD:304359	48/143 (34%)
mcm6l	NP_001020704.1	MCM_N	23..133	CDD:291233	29/111 (26%)
		MCM	116..651	CDD:214631	145/606 (24%)
		P-loop_NTPase	<441..528	CDD:304359	29/87 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	1	1.000	-	-		FOG0001226
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820