Protein Alignment rec and mcm6.2

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_001016221.1
• Gene: mcm6.2 / 548975
• XenbaseID: XB-GENE-5870537
• Length: 821
• Species: Xenopus tropicalis
• Alignment Length: 875
• Identity: 193/875 - (22%)
• Similarity: 337/875 - (38%)
• Gaps: 246/875 - (28%)

  Fly    74 GKRGRNAHLDCS--FLRPENYAAPEDGLQVQSIAVDNPRAYSGWRLYFLREKYEEGNELATRIMA 136
            ||.|.|.::..:  .:|||     .:.|.|....::          |:       ..:|||.|.
 Frog    40 GKDGSNLYVSAAEELVRPE-----RNTLVVNFTDIE----------YY-------NQQLATTIQ- 81

  Fly   137 VEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTV 201
             |.||:..||              ||.| ::|.|                  |.:|.:
 Frog    82 -EEYYRVYPH--------------LCRA-VRSFA------------------RQMGNI------- 105

  Fly   202 VVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSN 266
                                      |..::.|....||...:.|..:|.:::.||..|.|.|..
 Frog   106 --------------------------PANKEFYVAFSDFPARQKIRELSSAKIGTLLRISGQVVR 144

  Fly   267 VGEPSYSLTWQAFRCSRCQMEIAMRQRGTFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQII 331
            .......|....|.|..||..:...::.....:|..||...|..|..|.  ..:..:|....|.:
 Frog   145 THPVHPELVSGTFLCMDCQSVVKDVEQQFRYTQPTICKNPVCANRRRFT--LDTNKSRFVDFQKV 207

  Fly   332 RVEESSLNLVHDFETSMPAEMDVELRHDLVDAVRVGQEVVVTGILKL-------------QELGD 383
            |::|:...|...   ::|..:::.||.:.|:....|.....||.|.:             .|.|.
 Frog   208 RIQETQAELPRG---AIPRSVEIILRAEAVETAMAGDRCDFTGTLIVVPDISALAAGDARMETGA 269

  Fly   384 DTTTGD--TSNQMQPYLKAVSIRD------------------------------ASSIKREFSER 416
            ..|.|:  .|..:|. |||:.:||                              |.|||.:.:.:
 Frog   270 KVTGGEGFNSEGVQG-LKALGVRDLSYRLAFLACHVGATNPRFGGKDLREEDQTAESIKNQMTVQ 333

  Fly   417 DLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGG------KGAETEA-INVLLVGD 474
            :.|.:..::.:.|.:..|..|:.|.::|::..|...||.|.||      :|..... |||.:|||
 Frog   334 EWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEIKRGVLLMLFGGVPKTTMEGTSLRGDINVCIVGD 398

  Fly   475 PGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFA-----GRNKRVLQAGSLMMASGGGHC 534
            |...|::.|:...:.:.|..:.|||  |.||  .|:|.|     ..::.|::||:||:|. .|.|
 Frog   399 PSTSKSQFLKHVEEFSPRAVYTSGK--ASSA--AGLTAAVVKDEESHEFVIEAGALMLAD-NGVC 458

  Fly   535 TLDDVDKLASK-QAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINI 598
            .:|:.||:..| |..:.:.::.:.:::..||..|:..|:.|::|.|||..|:|:..:.|..|:|:
 Frog   459 CIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVGGRYERSKSLKHNVNL 523

  Fly   599 SPSLLREFHLVYILLDKPSE-RDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVP 662
            |..::..|.|.:||:|:.:| .|.::...:..|||
 Frog   524 SAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHA------------------------------ 558

  Fly   663 AAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDA 727
                         .|:..:::.|.::.                  |:::|.:||| ..|.:.::|
 Frog   559 -------------RNEESIERVYSIED------------------IQRYLLFARQ-FQPKITKEA 591

  Fly   728 SNAVLRYFLELKGSCNLDEDVSS-QIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTES 791
            ...::..:..|:.........|| :|...||.::|.||::.||:..|..|.|:||::...||::|
 Frog   592 EEFIVEQYRRLRQRDGSGVAKSSWRITVRQLESLIRLSESMARMHCSDEVQPKHVKEAFRLLSKS 656

  Fly   792 ITQTSLKEGSSRQGTRGGGGAGGGAGKSAQLRNFLELTKRRSAALGRRIFEFDELKEI----GTR 852
            |.:....:.|..||              ...:|..|.....:...|....|.::.:.|    .|.
 Frog   657 IIRVDTPDVSFDQG--------------EDEKNVEEEVNNANLNNGEEAMETNQDEPINDKPSTN 707

  Fly   853 AGILTGFSQLVEMANLGGYLLMKGANMYEV 882
            ||:...|::..:::||   |::....|.||
 Frog   708 AGLKMSFAEYKQISNL---LVLHMQKMEEV 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	151/681 (22%)
		MCM8	433..791	CDD:350665	95/372 (26%)
		MCM8_WHD	819..883	CDD:439328	15/68 (22%)
mcm6.2	NP_001016221.1	MCM_N	28..117	CDD:464206	28/166 (17%)
		MCM	123..658	CDD:475121	144/607 (24%)
		Arginine finger	529..532		0/2 (0%)
		MCM6_C	710..819	CDD:465688	7/28 (25%)