Protein Alignment rec and Mcm5

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Alignment Length: 730
• Identity: 162/730 - (22%)
• Similarity: 292/730 - (40%)
• Gaps: 170/730 - (23%)

  Fly   178 SLSEDIREHPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVP 242
            :|::.:.:.|...|.....|...|.        |..||.....|:::.....:....|.|
  Fly    78 TLADKLNKQPTEHLEIFEEAAREVA--------DEITAPRPEHEEHMHDIQILLSSNANP----- 129

  Fly   243 VESIEGISHSRVDTLFSIRGFV---SNVGEPSYSLTWQAFRCS-------------------RCQ 285
             .:|..:....|..|..|.|.:   |.:...:..::.|...||                   :|.
  Fly   130 -TNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLKVNPGLEGYALPRKCN 193

  Fly   286 MEIAMRQRGTFQP---RPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDF--E 345
            .|.|.|.:....|   .|.:||   ||   :|              |.::::|     :.||  :
  Fly   194 TEQAGRPKCPLDPFFIMPDKCK---CV---DF--------------QTLKLQE-----LPDFVPQ 233

  Fly   346 TSMPAEMDVELRHDLVDAVRVGQEVVVTGILKLQELGDDTTTGDTSNQM----QPYLKAVSI--- 403
            ..:|..:.:.....|.:.|..|..|::.||..::::|..:........:    .||::.|.|
  Fly   234 GEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRDGREKAVVGVRAPYMRVVGITVD 298

  Fly   404 -RDASSIKR--EFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGKG---- 461
             ..|.:|.|  ..:..:.|....:.|..:.::.|.||:||.::|....|.|....|.||..
  Fly   299 SEGAGAISRYSNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLP 363

  Fly   462 ---AETEAINVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFA------GRNK 517
               .....|||||:||||..|:::|:...::|....:.||| |:.:|   |:|.:      .||
  Fly   364 DGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGK-GSSAA---GLTASVMKDPQTRN- 423

  Fly   518 RVLQAGSLMMASGGGHCTLDDVDKLASKQAVLL-QCLQSEEVNLPLAGAFASFPAQPSVIACANP 581
            .|::.|::::|.||..| :|:.||:.....|.: :.::.:.:::..||...:..::.||:|.||.
  Fly   424 FVMEGGAMVLADGGVVC-IDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANS 487

  Fly   582 QRGQYDE--GRYLLQNINISPSLLREFHLVYILLDKPSE-RDMSLTAHVRALHAGARKRARIAAR 643
            ..|::|:  |.   :||:..|::|..|.:::|:.|...| ||::|..|:..:|..:.|.|
  Fly   488 IFGRWDDTKGE---ENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSA----- 544

  Fly   644 YALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILI 708
                              |:.                              |.||::.|   ...
  Fly   545 ------------------PSE------------------------------PAEGEISL---STF 558

  Fly   709 KKFLSYARQELNPVLNEDASNAV-LRYFLELKGSCN----LDEDVSSQIGAGQLLAIIHLSQARA 768
            ||::.|.|....|.|:|.|...: .||.|...|:..    .|:.:|..|...||.|:|.:|::.|
  Fly   559 KKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLA 623

  Fly   769 RLDLSHVVSPQHVRDVIALLTESITQTSLKEGSSRQGTRGGGGAGGGAGKSAQLRNFLELTKRRS 833
            ::.|....:.:||.:.:.|...| |..:...||.      .|..|....:..:..|.:|...:|.
  Fly   624 KIRLQPFATDEHVNEALRLFQVS-TLDAAMTGSL------AGAEGFTTEEDQETLNRIEKQLKRR 681

  Fly   834 AALGRRIFEFDELKE 848
            .|:|.::.|.:.|::
  Fly   682 FAIGSQVSEQNILQD 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	151/679 (22%)
		MCM8	433..791	CDD:350665	97/379 (26%)
		MCM8_WHD	819..883	CDD:439328	7/30 (23%)
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	9/54 (17%)
		MCM	128..648	CDD:214631	140/616 (23%)