Protein Alignment rec and mcm4

DIOPT Version :9

• Sequence 1: NP_001262615.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_944595.2
• Gene: mcm4 / 337598
• ZFINID: ZDB-GENE-030131-9544
• Length: 845
• Species: Danio rerio
• Alignment Length: 849
• Identity: 179/849 - (21%)
• Similarity: 323/849 - (38%)
• Gaps: 237/849 - (27%)

  Fly    24 AYRPYFYFRRNGRVIPAGGNRQPNQGEPGAP-----------DAPSVPPATRQPRGWSRTAGKRG 77
            |..|..|...:.||     ...|..|..|.|           .||.|...:....|.:..||.:|
Zfish    68 ASSPLMYGTPSSRV-----EGTPRSGIRGTPARQRADLGSVRKAPQVDMHSEPASGDAAVAGDQG 127

  Fly    78 RNAHL----------DC---------SFLRPENYAAPEDGLQVQSIAVDNPRAYSGWRLYFLREK 123
            ....|          .|         .|..|::......||.     ::.|       ||.  :|
Zfish   128 AGQRLVIWGTDVNVGTCKEKFQRFLQQFTDPDSREEENAGLD-----LNEP-------LYM--QK 178

  Fly   124 YEEGNELATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIRE--- 185
            .:|.:.:...::.|...:.:   |||..:.|....:|            :||.|:....:.|
Zfish   179 LDEISVVGEPVLNVNCTHIQ---TFDADLYRQLICYP------------QEVIPTFDMSVNELFF 228

  Fly   186 --HPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVPVESIEG 248
              .|            ..|:.||                          |..||...:...::..
Zfish   229 DRFP------------DSVLEHQ--------------------------IQVRPYSAIKTRNMRN 255

  Fly   249 ISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMR-QRGTFQPRPYQCKRSECVARD 312
            ::...:|.|.:|.|.|....:....:....|||..|.....:. .||.. ..|..|:........
Zfish   256 LNPEDIDQLITISGMVIRTSQLIPEMQEAFFRCQVCAFNTRVEVDRGRI-AEPAVCRNCNTTHSM 319

  Fly   313 EFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMD-----VELRHDLVDAVRVGQEVVV 372
            ..|..||.    .|.:|:|:::||        ...|||...     |...:||||.|:.|..|.:
Zfish   320 ALVHNRSV----FSDKQMIKLQES--------PEDMPAGQTPHTTVVYAHNDLVDKVQPGDRVNI 372

  Fly   373 TGILKLQELGDDTTTGDTSNQMQPYLKAVSIR----------DASSIKREFSERDLEAIVMINAE 427
            |||.:...:..:.......:..:.::.|:..|          |....::.|::..:..:..:.|:
Zfish   373 TGIYRAAPMRLNPRQSQVKSVYKTHIDAIHFRKTDEKRLHGLDEDGEQKLFTKERVALLKELAAK 437

  Fly   428 PNSFKLLVQSIAPEVYGHELPKAACLLSLLG---------GKGAETEAINVLLVGDPGIGKTKIL 483
            |:.::.|..::||.:|.||..|...||.|.|         |:|.....:|:||.||||..|:::|
Zfish   438 PDVYERLSSALAPSIYEHEDIKKGILLQLFGGTRKDFTQTGRGNFRAEVNILLCGDPGTSKSQLL 502

  Fly   484 QSCAQIAERGAHVSGKRGAQSAQQLGVTF-----AGRNKRVLQAGSLMMASGGGHCTLDDVDKLA 543
            |....:..||.:.|||    .:..:|:|.     ....:.|||.|:|:: |..|.|.:|:.||::
Zfish   503 QYVYNLVPRGQYTSGK----GSSAVGLTAYVMKDPETRQLVLQTGALVL-SDNGICCIDEFDKMS 562

  Fly   544 -SKQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFH 607
             :.::||.:.::.:.:::..||......|:.|::|.|||...|::..:..::||.:..:||..|.
Zfish   563 DNTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPVESQWNPKKTTIENIQLPHTLLSRFD 627

  Fly   608 LVYILLDKPSER-DMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTI 671
            |::::||...|. |..|..|:.:|:
Zfish   628 LIFLMLDPQDEAYDRRLAHHLVSLY---------------------------------------- 652

  Fly   672 KTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFL 736
                         |..::::    ||..||:   .::|.::::||..::|.|:|:||.|::..::
Zfish   653 -------------YQSEEQI----EEEHLDM---AVLKDYIAFARTTVHPRLSEEASQALIEAYV 697

  Fly   737 ELKGSCNLDEDVSSQIGAG---------QLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESI 792
            :::           :||:|         ||.::|.|::|.|::..|..|....|.:...|..|::
Zfish   698 DMR-----------KIGSGRGMVSAYPRQLESLIRLAEAHAKVRFSGKVETIDVEEAKRLHREAL 751

  Fly   793 TQTS 796
            .|::
Zfish   752 KQSA 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_001262615.1	RNR_PFL	<117..200	CDD:299130	15/87 (17%)
		MCM	243..792	CDD:214631	134/589 (23%)
		P-loop_NTPase	468..606	CDD:304359	43/143 (30%)
mcm4	NP_944595.2	MCM_N	147..269	CDD:291233	29/188 (15%)
		MCM	249..752	CDD:214631	134/591 (23%)
		P-loop_NTPase	487..626	CDD:304359	43/143 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820