Protein Alignment rec and Mcm2

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_001101343.2
• Gene: Mcm2 / 312538
• RGDID: 1305577
• Length: 905
• Species: Rattus norvegicus
• Alignment Length: 715
• Identity: 158/715 - (22%)
• Similarity: 293/715 - (40%)
• Gaps: 157/715 - (21%)

  Fly   167 KSDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTVVVNHQLD----------------------C 209
            :.|.::.|...:| ||::.|.:|.  .:|:|...:.::|:..                      |
  Rat   163 EEDEEMIESIENL-EDLKGHSVRE--WVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMC 224

  Fly   210 NDSTTAMVSTPEQ---------YVLPT---------------------PR----VRKIYARPDDF 240
            .::..::|...|.         |.||.                     |:    ...|:.|....
  Rat   225 KENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHL 289

  Fly   241 VPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGTF------QPR 299
            ..||.:..:....::.|....|.|::.......|:...:.||:|...:     |.|      :.:
  Rat   290 PLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFIL-----GPFCQSQNQEVK 349

  Fly   300 PYQCKRSECVARDEF-VPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDVELRHDLVDA 363
            |..|  .||.:...| :.:..:.|...   |.||::||...:.   ...:|...|..|..||||:
  Rat   350 PGSC--PECQSTGPFEINMEETIYQNY---QRIRIQESPGKVA---AGRLPRSKDAILLADLVDS 406

  Fly   364 VRVGQEVVVTGILKLQELGD-DTTTGDTSNQMQPYLKAVSIRDASSIKREFSERDLEAIVMINAE 427
            .:.|.|:.:|||......|. :||.|............|:.:|......|.::.|::.|..::.:
  Rat   407 CKPGDEIELTGIYHNNYDGSLNTTNGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITSLSKD 471

  Fly   428 PNSFKLLVQSIAPEVYGHELPKAACLLSLLGGK----GAETEA---INVLLVGDPGIGKTKILQS 485
            ....:.:..||||.:||||..|....|:|.||:    |.:.:.   |||||.||||..|::.|:.
  Rat   472 QQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKY 536

  Fly   486 CAQIAERGAHVSGKRGAQSAQQLGVT-FAGRN----KRVLQAGSLMMASGGGHCTLDDVDKLASK 545
            ..:::.|....:|    |.|..:|:| :..|:    :..|:||:|::|. .|.|.:|:.||:..:
  Rat   537 IEKVSSRAIFTTG----QGASAVGLTAYVQRHPVSREWTLEAGALVLAD-RGVCLIDEFDKMNDQ 596

  Fly   546 QAVLL-QCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLV 609
            ....: :.::.:.:::..||...|..|:.:|||.|||..|:||......:|::::..::..|.::
  Rat   597 DRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVL 661

  Fly   610 YILLD--KPSERDM----SLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDD 668
            .::.|  .|.:.:|    .:.:|||  |..:.|:                              |
  Rat   662 CVVRDTVDPVQDEMLARFVVGSHVR--HHPSNKK------------------------------D 694

  Fly   669 DTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLR 733
            :.:......:..|...|.    :|.||:|         ::||::.||::.:.|.||:...:.|.|
  Rat   695 EGLTNGGTTEPAMPNTYG----VEPLPQE---------VLKKYIIYAKERVRPKLNQMDQDKVAR 746

  Fly   734 YFLELKGSCNLDEDV---SSQIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESITQT 795
            .:.:|:     .|.:   |..|....:.::|.:::|.||:.|...|....|...|.::.||...|
  Rat   747 MYSDLR-----KESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMLESFIDT 806

  Fly   796  795
              Rat   807  806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	156/705 (22%)
		MCM8	433..791	CDD:350665	93/379 (25%)
		MCM8_WHD	819..883	CDD:439328
Mcm2	NP_001101343.2	MCM2_N	73..183	CDD:403724	6/20 (30%)
		MCM_N	198..288	CDD:464206	10/89 (11%)
		MCM	292..804	CDD:214631	138/579 (24%)