Protein Alignment rec and Mcm4

DIOPT Version :9

• Sequence 1: NP_001262615.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_387500.1
• Gene: Mcm4 / 29728
• RGDID: 3060
• Length: 862
• Species: Rattus norvegicus
• Alignment Length: 673
• Identity: 145/673 - (21%)
• Similarity: 276/673 - (41%)
• Gaps: 162/673 - (24%)

  Fly   172 LKEVWPSLSEDIREHPLRTLGTLSLAMHTV--------VVNHQLDCNDSTTAMVSTPEQYVLPTP 228
            :|....:|...:..:|...:.|..:|::.:        ::.||
  Rat   214 IKSFGKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQ---------------------- 256

  Fly   229 RVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRC----QMEIA 289
                |..||.:.:..:|:..::...:|.|.:|.|.|....:....:....|:|..|    ::|:
  Rat   257 ----IQVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEM- 316

  Fly   290 MRQRGTFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDV 354
              .||.. ..|..|...........:..||    ..|.:|:|:::||.    .|..........|
  Rat   317 --DRGRI-AEPCTCVHCHTTHSMALIHNRS----LFSDKQMIKLQESP----EDMPAGQTPHTVV 370

  Fly   355 ELRH-DLVDAVRVGQEVVVTGILKLQELGDDTTTGDTSNQMQPYLKAVSIR----------DASS 408
            ...| ||||.|:.|..|.||||.:...:..:....:..:..:.::..:..|          |..:
  Rat   371 LFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEA 435

  Fly   409 IKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLG---------GKGAET 464
            .::.|||:.::.:..::.:|:.::.|..::||.:|.||..|...||.|.|         |:|...
  Rat   436 EQKLFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFR 500

  Fly   465 EAINVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTF-----AGRNKRVLQAGS 524
            ..||:||.||||..|:::||....:..||.:.|||    .:..:|:|.     ....:.|||.|:
  Rat   501 AEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGK----GSSAVGLTAYVMKDPETRQLVLQTGA 561

  Fly   525 LMMASGGGHCTLDDVDKL-ASKQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDE 588
            |:: |..|.|.:|:.||: .|.::||.:.::.:.:::..||......|:.||:|.|||...|::.
  Rat   562 LVL-SDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNP 625

  Fly   589 GRYLLQNINISPSLLREFHLVYILLDKPSER-DMSLTAHVRALHAGARKRARIAARYALKPKMSD 652
            .:..::||.:..:||..|.|::::||...|. |..|..|:.:|:
  Rat   626 KKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLY--------------------- 669

  Fly   653 SMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQ 717
                                            |..::::|       .:.|...::|.:::||..
  Rat   670 --------------------------------YQSEEQVE-------QEFLDMAVLKDYIAYAHS 695

  Fly   718 ELNPVLNEDASNAVLRYFLELKGSCNLDEDVSSQIGAG---------QLLAIIHLSQARARLDLS 773
            .:.|.|:|:||.|::..::.::           :||:.         ||.::|.|::|.|::..|
  Rat   696 TIMPRLSEEASQALIEAYVNMR-----------KIGSSRGMVSAYPRQLESLIRLAEAHAKVRFS 749

  Fly   774 HVVSPQHVRDVIALLTESITQTS 796
            ..|....|.:...|..|::.|::
  Rat   750 DKVEAIDVEEAKRLHREALKQSA 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_001262615.1	RNR_PFL	<117..200	CDD:299130	5/27 (19%)
		MCM	243..792	CDD:214631	134/588 (23%)
		P-loop_NTPase	468..606	CDD:304359	45/143 (31%)
Mcm4	NP_387500.1	MCM_N	165..286	CDD:291233	14/97 (14%)
		MCM	266..769	CDD:214631	134/590 (23%)
		P-loop_NTPase	504..643	CDD:304359	45/143 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820