Protein Alignment rec and Mcm5

DIOPT Version :9

• Sequence 1: NP_001262615.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: XP_038953490.1
• Gene: Mcm5 / 291885
• RGDID: 1306616
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 856
• Identity: 188/856 - (21%)
• Similarity: 323/856 - (37%)
• Gaps: 243/856 - (28%)

  Fly    49 GEPGAPDAPSVPPATRQPRGWSRTAGKRGRNAHLDCSFLRPENYAAPEDGLQVQSIAVDNPRAYS 113
            |:|||.:.                   :.|.:||...|..
  Rat    17 GDPGAEEG-------------------QARKSHLQKRFKE------------------------- 37

  Fly   114 GWRLYFLREKYEEGNELATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVW-- 176
                 |||: |..|.:             |...||.:   ||.         :|....|.|.|
  Rat    38 -----FLRQ-YRVGTD-------------RTGFTFKY---RDE---------LKRHYNLGEYWIE 71

  Fly   177 ------PSLSEDIREH----PLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVR 231
                  .|..|::.::    |...|..|..|...|.        |..|......::.:.....:.
  Rat    72 VEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVA--------DEVTRPRPAGDELLQDIQVML 128

  Fly   232 KIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQ---MEIAMRQ- 292
            |..|.|      .||..:....:..|..|.|.:.:........|..:.:|..|.   ..||||.
  Rat   129 KSDASP------SSIRILKSDMMSHLVKIPGIIISASAVRAKATRISIQCRSCHNTLTNIAMRPG 187

  Fly   293 -RGTFQPRPY---QCKRSECVARDEFVPLRSSPYTRLSIR------QIIRVEESSLNLVHDFETS 347
             .|...||..   |..|.:|       ||  .||..:..:      |.::::|....:.|.   .
  Rat   188 LEGYALPRKCNMDQAGRPKC-------PL--DPYFIMPDKCKCVDFQTLKLQELPDAVPHG---E 240

  Fly   348 MPAEMDVELRHDLVDAVRVGQEVVVTGILKLQELG-------DDTTTGDTSNQMQPYLKAVSIR- 404
            ||..|.:.....|.|.|..|..|.:.||..:::.|       |....|..|:    |::.:.|:
  Rat   241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGMNPSKGRDRVGVGIRSS----YIRVLGIQV 301

  Fly   405 DASSIKREF----SERDLEAIVMINAEPNSFKLLVQSIAPEVY-GHELPKA-ACLLSLLGGK--- 460
            |.....|.|    |.::.|....:.|.||.::|:.:|::|.:: |.::.|| |||  |.||.
  Rat   302 DTDGSGRSFAGSVSPQEEEEFRRLAALPNIYELVSRSVSPSIFGGMDMKKAIACL--LFGGSRKR 364

  Fly   461 ---GAETEA-INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTF------AGR 515
               |..... ||:|::||||..|:::|:...:.:..|.:.||| |:.:|   |:|.      :.|
  Rat   365 LPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGK-GSSAA---GLTASVIRDPSSR 425

  Fly   516 NKRVLQAGSLMMASGGGHCTLDDVDKLASKQAVLL-QCLQSEEVNLPLAGAFASFPAQPSVIACA 579
            | .:::.|::::|.||..| :|:.||:.....|.: :.::.:.:::..||...:..::.||:|.|
  Rat   426 N-FIMEGGAMVLADGGVVC-IDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAA 488

  Fly   580 NPQRGQYDE--GRYLLQNINISPSLLREFHLVYILLDKPS-ERDMSLTAHVRALHAGARKRARIA 641
            |...|::||  |.   .||:..|::|..|.:::|:.|:.: ||||.|..||..||..|..:.:..
  Rat   489 NSVFGRWDETKGE---DNIDFMPTILSRFDMIFIVKDEHNEERDMMLAKHVITLHVSALTQTQAV 550

  Fly   642 ARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPI 706
                                                                   ||::||..
  Rat   551 -------------------------------------------------------EGEIDLAK-- 558

  Fly   707 LIKKFLSYARQELNPVLNEDASNAVL-RYFLELKGSCNLDEDV----SSQIGAGQLLAIIHLSQA 766
             :|||::|.|....|.|:.:|:..:. ||.:...|:...:.|:    |..|...||.||:.:::|
  Rat   559 -MKKFIAYCRARCGPRLSAEAAEKLKNRYIIMRSGARQHERDIDRRSSIPITVRQLEAIVRIAEA 622

  Fly   767 RARLDLSHVVSPQHVRDVIALLTESITQTSLKEGSSRQGTRGGGGAGGGAGKSAQLRNFLELTKR 831
            .:::.|....:...|.:.:.|...|....:|....|       |..|....:..::.:.:|...:
  Rat   623 LSKMKLQPFATEADVEEALRLFQVSTLDAALSGNLS-------GVEGFTTQEDQEMLSRIEKQLK 680

  Fly   832 RSAALGRRIFE 842
            |..|:|.::.|
  Rat   681 RRFAIGSQVSE 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_001262615.1	RNR_PFL	<117..200	CDD:299130	20/94 (21%)
		MCM	243..792	CDD:214631	144/598 (24%)
		P-loop_NTPase	468..606	CDD:304359	42/146 (29%)
Mcm5	XP_038953490.1	MCM_N	32..129	CDD:405270	24/160 (15%)
		MCM	133..649	CDD:214631	146/606 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910