Protein Alignment rec and mcm5

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_001342928.1
• Gene: mcm5 / 2542477
• PomBaseID: SPAC1B2.05
• Length: 720
• Species: Schizosaccharomyces pombe
• Alignment Length: 666
• Identity: 150/666 - (22%)
• Similarity: 289/666 - (43%)
• Gaps: 146/666 - (21%)

  Fly   198 MHTVVVNHQLDCNDSTTAMVSTPEQYVLP-------TPRVRKIYARPDDF---VP---------- 242
            |..:.:.|.:..|:....::.:....:||       |...|.:|...::.   :|
pombe    63 MLNIDLRHLISYNEDLAHLLLSQPTDILPLFESAVTTVAKRLLYRSQENASTNIPTCQVTLRYDA 127

  Fly   243 -VESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGTFQ----PRPYQ 302
             :..|..::.|.:..|..:.|.:......|...|.....|..|:....::..|.|.    ||..:
pombe   128 NILPIRNLTASHISKLVRVPGIIIGASTLSCRATALHLVCRNCRATRILQISGGFSGVQLPRVCE 192

  Fly   303 C-----KRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDV-EL-RHDL 360
            .     ::.:| ..|.|: :..|..|.:. :|:::::|:            |..:.| || ||.|
pombe   193 APVLDGEKKDC-PMDPFI-IDHSKSTFID-QQVLKLQEA------------PDMVPVGELPRHIL 242

  Fly   361 VDAVRV-------GQEVVVTGILKLQELGDDTTTGDTSNQMQPYLKAVSIR----DASSIKREFS 414
            ::|.|.       |...|:|||..:.:......:|..:.: .||::.|.|:    |.|.....||
pombe   243 LNADRYLTNQITPGTRCVITGIFSIFQNKSVKASGAVAIR-NPYIRVVGIQMDSNDGSKSTPLFS 306

  Fly   415 ERDLEAIVMINAEPNSFKLLVQSIAPEVYGH-ELPKA-ACLLSLLGGKGAETEA------INVLL 471
            |.:.|..:.|:..||.:.::..||:|.:||: ::.|| |||| ..|.|....:.      |||||
pombe   307 EEEEEEFLEISRTPNLYDIISNSISPAIYGNVDIKKAIACLL-FSGSKKILPDGMRLRGDINVLL 370

  Fly   472 VGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRNKRV-----LQAGSLMMASGG 531
            :||||..|::.|:...::|....:.||| |:.:|   |:|.:.:...|     |:.|::::|.||
pombe   371 LGDPGTAKSQFLKFVERLAPIAVYTSGK-GSSAA---GLTASIQRDSVTREFYLEGGAMVLADGG 431

  Fly   532 GHCTLDDVDKLASKQAVLL-QCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQN 595
            ..| :|:.||:..:..|.: :.::.:.:::..||......::.||:|.|||..|:||:.:...:|
pombe   432 IVC-IDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPIFGRYDDMKTPGEN 495

  Fly   596 INISPSLLREFHLVYILLDKPSE-RDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSL 659
            |:...::|..|.:::|:.|:..| :|.::..||..||.
pombe   496 IDFQSTILSRFDMIFIVKDEHDETKDRNIARHVINLHT--------------------------- 533

  Fly   660 NVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLN 724
                        ..::.::::...:...||                  .:::::|.|.:..|.|:
pombe   534 ------------NLQESSETLAIGEIPFDK------------------FRRYINYCRHKCAPNLD 568

  Fly   725 EDASNAVLRYFLELKGSCNLDEDVSSQ-----IGAGQLLAIIHLSQARARLDLSHVVSPQHVRDV 784
            .:|:..:...|:.::...:..|..|:.     |...||.|||.::::.|::.||.:.|..|..:.
pombe   569 AEAAEKLSSQFVAIRKRVHQSEQDSNSRSTIPITVRQLEAIIRITESLAKMSLSPIASEAHATEA 633

  Fly   785 IAL-LTESI---TQTS 796
            |.| ||.::   ||:|
pombe   634 IRLFLTSTLAAATQSS 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	150/666 (23%)
		MCM8	433..791	CDD:350665	91/378 (24%)
		MCM8_WHD	819..883	CDD:439328
mcm5	NP_001342928.1	MCM_N	34..124	CDD:464206	9/60 (15%)
		MCM	128..642	CDD:214631	138/592 (23%)