Protein Alignment rec and mcm-7

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_504199.1
• Gene: mcm-7 / 178831
• WormBaseID: WBGene00003159
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 721
• Identity: 154/721 - (21%)
• Similarity: 289/721 - (40%)
• Gaps: 169/721 - (23%)

  Fly    97 DGLQVQSIAVDNPRAYSGWRLYFLREKYEE--GNELATRIMAVEAYYQRNPHTFDFVMIRDRGFF 159
            |.|::......|.:.|.......:.:..::  |::.|..|.|::||..:..|     |.|:.|
 Worm    67 DALELSEAITSNTKRYEVLFKDTISDMIQDYLGDKQAPVIDALDAYMFQRLH-----MDRNEG-- 124

  Fly   160 PLCAAGIKSDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYV 224
                      |..:||  ||.:..:::|.:.|...
 Worm   125 ----------AANEEV--SLQDKRKKYPPQLLQRF------------------------------ 147

  Fly   225 LPTPRVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIA 289
                   ::|...||......:..|..:.:..|.|::|.|....|....:....:.|..|..|:.
 Worm   148 -------EVYFTTDDAAHETCVRNIKATEIGHLVSMKGVVIRATEVKPCVEVMTYTCDTCAAEVY 205

  Fly   290 MRQRG-TFQPRPYQCKRSECVARDE----FVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMP 349
            ...:| .|.| |..|...|||....    .:.||.|.:.:.   |.::::|.|..:.   ..|:|
 Worm   206 QPVKGMQFTP-PVNCPNKECVEAKANGRLHMQLRGSKFVKF---QELKIQELSEQVP---VGSIP 263

  Fly   350 AEMDVELRHDLVDAVRVGQEVVVTGI-LKLQELGDDTTTG---DTSNQMQPYLKA--VSIRDASS 408
            ..|.|.:..::......|..|.|:|: |.:.:.|...|.|   ||      ||:|  ::..|.:.
 Worm   264 RTMTVHVYGEMTRKCNTGNVVHVSGVFLPIMQSGFRPTGGLVADT------YLEAHYINNLDDNP 322

  Fly   409 IKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETE------AI 467
            ........:||   ::..:.::::.|..|||||::||...|...|::|:||....:.      .|
 Worm   323 TFNGVQSAELE---VLRRKGDNYETLAASIAPEIFGHVDVKKCLLMALVGGNDNSSNGMKIRGCI 384

  Fly   468 NVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRNKRV-----LQAGSLMM 527
            |||::||||:.|:::|....::|.|..:.:| ||:..   :|:|.|.....|     |:.|:|::
 Worm   385 NVLMMGDPGVAKSQLLGYVNRLAPRSQYTTG-RGSSG---VGLTAAVMKDPVTGEMSLEGGALVL 445

  Fly   528 ASGGGHCTLDDVDKLAS-KQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRY 591
            |. ||.|.:|:.||:.. .:..:.:.::.:.:::..||...:..|:.::||.|||..|:|:..|.
 Worm   446 AD-GGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAGIMTTLNARTAIIAAANPAYGRYNPNRS 509

  Fly   592 LLQNINISPSLLREFHLVYILLDKPS-ERDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMC 655
            :.||:::..:||..|.|:.::.||.. |.|..|..|:..:|...                    |
 Worm   510 IEQNVDLPAALLSRFDLILLMQDKADRENDKILAEHITYVHQHG--------------------C 554

  Fly   656 EVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYAR---Q 717
            .                                      |.....||:....:::::|..:   .
 Worm   555 H--------------------------------------PNREKKDLISLETLREYISLCKTYTP 581

  Fly   718 ELNPVLNEDASNAVLRYFLELKGSCNLDEDVSSQIGAGQLLAIIHLSQARARLDLSHVVSPQHVR 782
            .::|.|.|    .::..::|::.......| .:.:....:|.|:.::.|||:|.||.:|....|.
 Worm   582 TVDPALRE----RIVEAYVEMRRDARYSSD-PTFVSPRMILGIVRMATARAKLRLSTIVDESDVE 641

  Fly   783 DVIALL 788
            :.:.|:
 Worm   642 EALRLM 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	137/639 (21%)
		MCM8	433..791	CDD:350665	87/372 (23%)
		MCM8_WHD	819..883	CDD:439328
mcm-7	NP_504199.1	MCM_N	14..107	CDD:464206	6/39 (15%)
		MCM	162..651	CDD:475121	130/570 (23%)