Protein Alignment rec and mcm-6

DIOPT Version :9

• Sequence 1: NP_001262615.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_001023011.1
• Gene: mcm-6 / 176385
• WormBaseID: WBGene00003158
• Length: 810
• Species: Caenorhabditis elegans
• Alignment Length: 736
• Identity: 170/736 - (23%)
• Similarity: 299/736 - (40%)
• Gaps: 194/736 - (26%)

  Fly   120 LREKYEEGNELATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIR 184
            ::..|:..|.|||   .:|..|.|                               |:|.:.|
 Worm    59 MQHLYKFSNNLAT---TIELQYYR-------------------------------VYPFMCE--- 86

  Fly   185 EHPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVPVESIEGI 249
                        |:|...::   .|::|....:...:.||    .:..:.|:       ..:..:
 Worm    87 ------------ALHLATLD---ACDESERQQMFKKQLYV----SLFNLDAK-------TKVREL 125

  Fly   250 SHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGTFQPRPYQCKRSECVARDEF 314
            |..:|..|..|.|.:.........|:...|.|..|.:.....|:.....:|.:|...:|:.|..|
 Worm   126 SADKVGGLVRIAGQIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKCANPQCMNRTRF 190

  Fly   315 -VPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDVELRHDLVDAVRVGQEVVVTG-ILK 377
             :.:.||.:...   |.||::|:...|...   |:|..:||.:|.::|:.|:.|.:..:.| ::.
 Worm   191 SLDVNSSTFVDF---QKIRIQETQAELPRG---SIPRTVDVIVRGEMVETVQPGDKCDIVGTLIV 249

  Fly   378 LQELGDDTTTG---DTSNQMQ----------PYLKAVSIR----------------------DAS 407
            :.::...:|.|   :||||.:          ..|||:.:|                      |||
 Worm   250 IPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDAS 314

  Fly   408 SIKRE---------FSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGG--KG 461
            ....|         .|..|...:..::.:....|.:|.|:.|.:||:...|...||.||||  |.
 Worm   315 GAVEETDYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVAKK 379

  Fly   462 AETEA------INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRNKR-- 518
            :..|.      |||.|||||...|:::|::..:.:.|..:.|||  |.||  .|:|.|.....
 Worm   380 SRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGK--ASSA--AGLTAAVVKDEES 440

  Fly   519 ---VLQAGSLMMASGGGHCTLDDVDKLASK-QAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACA 579
               |::||:||:|. .|.|.:|:.||:..| |..:.:.::.:.:::..||..|:..|:.|::|.|
 Worm   441 FEFVIEAGALMLAD-NGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARASILAAA 504

  Fly   580 NPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSERDMSLTAHVRALHAGARKRARIAARY 644
            ||..|:||..|.|..|:.:|..::..|.|.::|:|:.:|                      ...|
 Worm   505 NPVNGRYDRSRPLKYNVQMSAPIMSRFDLFFVLVDECNE----------------------VTDY 547

  Fly   645 ALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIK 709
            |:..::.|              :...|....:.||:    |.:|.                  ||
 Worm   548 AIARRILD--------------NHRAISEHTERDSV----YKIDD------------------IK 576

  Fly   710 KFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSS-QIGAGQLLAIIHLSQARARLDLS 773
            |::::||. ..|.:::.|:..::|.:.:|:.|.:.:...|| :|...||.:::.||:|.|||...
 Worm   577 KYIAFARC-FKPKISDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARLHCG 640

  Fly   774 HVVSPQHVRDVIALLTESITQ 794
            ..|..:||.....||.:||.:
 Worm   641 KEVLVEHVEKAAELLNKSIVR 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_001262615.1	RNR_PFL	<117..200	CDD:299130	12/79 (15%)
		MCM	243..792	CDD:214631	150/609 (25%)
		P-loop_NTPase	468..606	CDD:304359	48/143 (34%)
mcm-6	NP_001023011.1	MCM_N	23..138	CDD:291233	22/141 (16%)
		MCM	119..660	CDD:214631	151/617 (24%)
		P-loop_NTPase	<448..535	CDD:304359	29/87 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	1	1.000	-	-		FOG0001226
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920