Protein Alignment rec and Mcm6

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_032593.1
• Gene: Mcm6 / 17219
• MGIID: 1298227
• Length: 821
• Species: Mus musculus
• Alignment Length: 769
• Identity: 176/769 - (22%)
• Similarity: 308/769 - (40%)
• Gaps: 170/769 - (22%)

  Fly   166 IKSDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRV 230
            :.|.|.|::....||..|:|...|....|..|:.|.|.:.:                   ..|..
Mouse    62 VVSFADLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRK-------------------EIPFA 107

  Fly   231 RKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGT 295
            :..|....|......|..::.||:..|..|.|.|.........|....|.|..||..|...::..
Mouse   108 KDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQF 172

  Fly   296 FQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDVELRHDL 360
            ...:|..|:...|..|..|  |..:..:|....|.:|::|:...|...   |:|..::|.||.:.
Mouse   173 KYTQPNICRNPVCANRKRF--LLDTNKSRFVDFQKVRIQETQAELPRG---SIPRSLEVILRAEA 232

  Fly   361 VDAVRVGQE-------VVVTGILKLQELGDDTTTGDTSNQMQPY-------LKAVSIRD------ 405
            |::.:.|..       :||..:.||...|....|....:....|       |:|:.:||
Mouse   233 VESAQAGDRCDFTGALIVVPDVSKLSTPGARAETNSRVSGADGYETEGIRGLRALGVRDLSYRLV 297

  Fly   406 ------------------------ASSIKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHE 446
                                    |.|||.:.:.::.|.:..::.:.|.:..|..|:.|.::|::
Mouse   298 FLACHVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGND 362

  Fly   447 LPKAACLLSLLG------GKGAETEA-INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQS 504
            ..|...||.|.|      |:|..... |||.:||||...|::.|:...:.:.|..:.|||  |.|
Mouse   363 EVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGK--ASS 425

  Fly   505 AQQLGVTFA-----GRNKRVLQAGSLMMASGGGHCTLDDVDKLASK-QAVLLQCLQSEEVNLPLA 563
            |  .|:|.|     ..::.|::||:||:|. .|.|.:|:.||:..: |..:.:.::.:.:::..|
Mouse   426 A--AGLTAAVVRDEESHEFVIEAGALMLAD-NGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKA 487

  Fly   564 GAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSE-RDMSLTAHV 627
            |..|:..|:.|::|.|||..|.||..:.|.||||:|..::..|.|.:||:|:.:| .|.::...:
Mouse   488 GVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRI 552

  Fly   628 RALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLE 692
            ..||:                                       :.|:..|.:    |.||.
Mouse   553 VDLHS---------------------------------------RIEESIDRV----YSLDD--- 571

  Fly   693 VLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSS-QIGAGQ 756
                           |:::|.:||| ..|.:::::.:.::..:..|:.........|| :|...|
Mouse   572 ---------------IRRYLLFARQ-FKPKISKESEDFIVEQYKRLRQRDGSGVTKSSWRITVRQ 620

  Fly   757 LLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESITQTSL-------KEGSSRQGTRGGGGAGG 814
            |.::|.||::.||:.....|.|:||::...||.:||.:...       :|....:...|.||..|
Mouse   621 LESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMETDEGQGGVNG 685

  Fly   815 GAGKSAQLRNFLELTKRRSAALGRRIFEFDELKEIGTRAGILTGFSQLVEMANL 868
            .|...|.:..|...::             |..:|..::..:..||::...::||
Mouse   686 HADSPAPVNRFNGSSE-------------DASQETVSKPSLRLGFAEYCRISNL 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	159/687 (23%)
		MCM8	433..791	CDD:350665	97/372 (26%)
		MCM8_WHD	819..883	CDD:439328	8/50 (16%)
Mcm6	NP_032593.1	MCM_N	27..116	CDD:464206	14/72 (19%)
		MCM	119..657	CDD:475121	146/609 (24%)
		Arginine finger	528..531		0/2 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	676..708		9/44 (20%)
		MCM6_C	711..817	CDD:465688	4/16 (25%)