Protein Alignment rec and Mcm6

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: XP_319406.4
• Gene: Mcm6 / 1279642
• VectorBaseID: AGAMI1_000689
• Length: 814
• Species: Anopheles gambiae
• Alignment Length: 868
• Identity: 189/868 - (21%)
• Similarity: 323/868 - (37%)
• Gaps: 285/868 - (32%)

  Fly    96 EDGLQVQSIAVDNPRAYSGWRLYFLREKYEEG------------------------------NEL 130
            |.|::.|.:.:|           ||.|..|:|                              ..|
Mosquito    16 EVGVRCQKLFLD-----------FLEEFKEDGEIKYLKTVENLVNPDRSTLEVSFEDVENYNQTL 69

  Fly   131 ATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIREHPLRTLGTLS 195
            ||.|  :|.||:..|:              ||              .|:|..:|:.
Mosquito    70 ATAI--IEEYYRIFPY--------------LC--------------QSVSNFVRDR--------- 95

  Fly   196 LAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVPV---ESIEGISHSRVDTL 257
                              |::..:.|.||              .||.|   ..:..:|.|::.||
Mosquito    96 ------------------TSLKKSKECYV--------------SFVDVPTRHKVRELSTSKIGTL 128

  Fly   258 FSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIA-MRQRGTFQPRPYQCKRSECVARDEFVPLRSSP 321
            ..|.|.|.........|....|.|..||.||. :.|:..| ..|..|:...|..|..|:
Mosquito   129 IRISGQVVRTHPVHPELVLGTFVCLDCQTEIRDVEQQFKF-TNPTICRNPVCANRRRFM------ 186

  Fly   322 YTRLSIR-------QIIRVEESSLNLVHDFETSMPAEMDVELRHDLVDAVRVGQEVVVTGIL--- 376
               |.:.       |.:|::|:...|...   .:|..::|.||.::|:.|:.|.....||.|
Mosquito   187 ---LEVDKSLFIDFQKVRIQETQAELPRG---CIPRSVEVILRAEMVETVQAGDRYDFTGTLIVI 245

  Fly   377 ----KLQ------ELGDDTTTGDTSNQMQPYLKAVSIRD--------ASSI-------------- 409
                .||      |:|.....||.:.:....|||:.:||        |.|:
Mosquito   246 PDVGALQLPGAKAEIGSRHKQGDNAAEGVRGLKALGMRDLNYKMAFLACSVQVTSSRFGGTDMPM 310

  Fly   410 --------KREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETEA 466
                    |.:.:..:...:..::.:|..::.|:.|:.|.:||::..|...||.|.||....|:.
Mosquito   311 SEVTSQIMKDQMTPAEWNKVYEMSRDPRLYQNLINSLFPSIYGNDEVKRGILLMLFGGVAKTTQE 375

  Fly   467 -------INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFA-GRNKR----V 519
                   |||.:||||...|::.|:..:..:.|..:.|||  |.||  .|:|.| .|::.    |
Mosquito   376 KTTLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAVYTSGK--ASSA--AGLTAAVVRDEESFDFV 436

  Fly   520 LQAGSLMMASGGGHCTLDDVDKL-ASKQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQR 583
            ::||:||:|. .|.|.:|:.||: ...|..:.:.::.:.:::..||..|:..|:.|::|.|||..
Mosquito   437 IEAGALMLAD-NGICCIDEFDKMDPHDQVAIHEAMEQQTISIAKAGVRATLNARTSILAAANPIG 500

  Fly   584 GQYDEGRYLLQNINISPSLLREFHLVYILLDKPSERDMSLTAHVRALHAGARKRARIAARYALKP 648
            |:||..:.|.|||.::..::..|.|.:||:|:.:|                      ...||:..
Mosquito   501 GRYDRSKSLQQNIQLTAPIMSRFDLFFILVDECNE----------------------VVDYAIAR 543

  Fly   649 KMSD--SMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKF 711
            |:.|  |..|.||         |.:.:.:|                               :.::
Mosquito   544 KIVDLHSHIEHSL---------DQVYSRED-------------------------------VLRY 568

  Fly   712 LSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSS------QIGAGQLLAIIHLSQARARL 770
            :.:||| ..||:..:|...::..:..|:     ..|..:      :|...||.::|.||:|.|::
Mosquito   569 IMFARQ-FKPVIQPEAMALLVENYGHLR-----QRDTGTTGKSTWRITVRQLESMIRLSEAMAKM 627

  Fly   771 DLSHVVSPQHVRDVIALLTESITQTSL-------KEGSSRQGTRGGGGAGGGAGKSAQLRNFLEL 828
            :.|..|:.:||::...||.:||.:...       :||...:...   ..|....:.....|..|.
Mosquito   628 ECSEEVTERHVKEAYRLLNKSIIRVEQPDIHLDEEEGEENENVM---DIGEETPEDTPRTNETEE 689

  Fly   829 TKRRSAALGRR--IFEFDELKEI 849
            ..:.:.|:.::  ...|:|.|.:
Mosquito   690 NDQDTPAVAKKKLTLSFEEYKNL 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	161/703 (23%)
		MCM8	433..791	CDD:350665	98/378 (26%)
		MCM8_WHD	819..883	CDD:439328	6/33 (18%)
Mcm6	XP_319406.4	None