Protein Alignment rec and mcm8

DIOPT Version :10

• Sequence 1: NP_732072.1
• Gene: rec / 49241
• FlyBaseID: FBgn0003227
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: XP_002665161.2
• Gene: mcm8 / 100333576
• ZFINID: ZDB-GENE-120927-1
• Length: 852
• Species: Danio rerio
• Alignment Length: 927
• Identity: 265/927 - (28%)
• Similarity: 415/927 - (44%)
• Gaps: 140/927 - (15%)

  Fly     7 RGGAPSRFVRGRG--RGGGAYRPYFYFRRNGRVIPAGGNRQPNQGEPGAPDAPSVPPATRQPRGW 69
            |||..|    |.|  ||||.:|               |.|..:.|               |.|||
Zfish    12 RGGNSS----GSGGWRGGGGWR---------------GGRGWSNG---------------QYRGW 42

  Fly    70 S----RTAGKRGRNAHLDCSFLRPENYA--------APE-DGLQVQSIAVDNPRAYSGWRLYFLR 121
            .    ...|..||.           ||:        ||: ...:|....:|....|.|||||| .
Zfish    43 RGRQWSGGGGGGRG-----------NYSNNNTQKGNAPQVSQARVTQATLDITCPYKGWRLYF-S 95

  Fly   122 EKYEEGNELATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIREH 186
            |.:.|.:....:|...|.|:......:|...|..:|...:....:.|:.|:....|.|:.|::|.
Zfish    96 EGFVESSPYVEKIKVFEQYFTSQIDLYDKDEIERKGSILVDYKDLLSNKQVSHSLPDLARDLKEM 160

  Fly   187 PLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPE--QYVLPTPRVRKIYARPDDFVPVESIEGI 249
            |.:.|..|.:|:|.|:.   ||.......:....|  ..:.|...:..|.||..::.|:..::.:
Zfish   161 PEKILDCLGVAIHQVLT---LDLERHAAELQGQEELPAGIRPIINIPHISARLYNYEPLTPLKSL 222

  Fly   250 SHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGTFQPRPYQCKRSECVARDEF 314
            ..:.......|||.|..|..........||.|:.|....::.........|.:|.:|||..| .|
Zfish   223 RANLYGKFVVIRGTVVRVSNIKPLCMKLAFVCNSCGDTQSVTLPDGKYTMPTKCLQSECRGR-SF 286

  Fly   315 VPLRSSPYTRLSIRQIIRVEESSLNLVHDFETS--MPAEMDVELRHDLVDAVRVGQEVVVTGILK 377
            .|.||||:|.....|.|:|:|.   :..|...|  :|..::.||..||||:...|..|.:||::|
Zfish   287 TPNRSSPFTLTVDWQTIKVQEL---MSGDQRESGRIPRTIECELTQDLVDSCVPGDMVTITGVIK 348

  Fly   378 L-QELGDDTTTGD------------TSNQMQPYLKAVSIRDASSIKREFSERDLEAIVMINAEPN 429
            : .|.|......|            .||......||||..:......|||.:||.||..|.|:.:
Zfish   349 VSNEEGSTRNKKDKCMFLLYIQANSVSNSKGQKSKAVSESEGQGPSVEFSIKDLYAIQEIQAQED 413

  Fly   430 SFKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETEAIN---------VLLVGDPGIGKTKILQS 485
            .|||:|.|:.|.:|||.|.||...|:|.||.....:..|         :|:|||||:||:::||:
Zfish   414 LFKLIVNSLCPVIYGHLLVKAGLALALFGGCQKYVDDKNRIPIRGDPHMLIVGDPGLGKSQMLQA 478

  Fly   486 CAQIAERGAHVSGKRGAQSAQQLGVTF-----AGRNKRVLQAGSLMMASGGGHCTLDDVDKLASK 545
            ...:|.||.:|.|.....|    |:|.     :|.....|:||:|::.. .|.|.:|:.||:.|:
Zfish   479 VCNVAPRGVYVCGNTTTTS----GLTVSLSRDSGSGDYALEAGALVLGD-QGICCIDEFDKMGSQ 538

  Fly   546 QAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVY 610
            ...||:.::.:.::|..||...:.||:.|:||.|||..|.|::|:.:.:|:.:..:||..|.||:
Zfish   539 HQALLEAMEQQSISLAKAGIVCTLPARTSIIAAANPVGGHYNKGKTVSENLKMGSALLSRFDLVF 603

  Fly   611 ILLDKPSE-RDMSLTAHVRALHAGARKRARIAARYALK---PKMSDSMCEVSLNVPAAGKDDDTI 671
            ||||.|:| .|..|:.||.|:.||  |...::...|.:   .:.|.|:.|||...|.|    ||:
Zfish   604 ILLDTPNEDHDHLLSEHVMAMRAG--KSGAVSGAAATRFNTHESSISILEVSSEKPLA----DTL 662

  Fly   672 KTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFL 736
            |                    ::|.|. .|.:|..|::|::.|||..::|.|:.:|:..:..::|
Zfish   663 K--------------------LVPGEA-FDPIPHQLLRKYVGYARHYVHPTLSAEAAQVLQDFYL 706

  Fly   737 ELKGSCNLDEDVSSQIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESITQTSLKEGS 801
            ||:.. |...| |:.|...||.::|.|::||||::|....:.....||:.::..|:|.|...|..
Zfish   707 ELRKQ-NQTAD-STPITTRQLESLIRLTEARARVELREKATQSDAEDVVEIMKHSLTDTYSDEFG 769

  Fly   802 SRQGTRGGGGAGGGAGKSAQLRNFLELTKRRSAALGRRIFEFDELKEIGTRAGI-LTGFSQLVEM 865
            .....|  ...|.|....::::.|:....:.:....:.:||..:|:::.....| :..|...:..
Zfish   770 RLDFDR--SQLGSGMSNRSKVKKFVSALNKLAERTSKSMFELQDLRQLAKDLQIQVVDFEGFICA 832

  Fly   866 ANLGGYLLMKGANMYEV 882
            .|..||||.||..||::
Zfish   833 LNEQGYLLKKGHRMYQL 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rec	NP_732072.1	Mcm2	177..799	CDD:440854	202/656 (31%)
		MCM8	433..791	CDD:350665	121/375 (32%)
		MCM8_WHD	819..883	CDD:439328	15/65 (23%)
mcm8	XP_002665161.2	Mcm2	100..844	CDD:440854	227/786 (29%)