Protein Alignment mod(mdg4) and BACH2

DIOPT Version :9

• Sequence 1: NP_788698.1
• Gene: mod(mdg4) / 49228
• FlyBaseID: FBgn0002781
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: XP_024302278.1
• Gene: BACH2 / 60468
• HGNCID: 14078
• Length: 927
• Species: Homo sapiens
• Alignment Length: 749
• Identity: 135/749 - (18%)
• Similarity: 229/749 - (30%)
• Gaps: 201/749 - (26%)

  Fly     3 DDEQFSLCWNNFN-----------------------------TNLSAGFHESLCRGDLVDVSLAA 38
            :..|.|..||.|.                             ||:..|.::...:..|.||:|..
Human    65 ETSQISRNWNVFKSWQSQGVNGMSVDEKPDSPMYVYESTVHCTNILLGLNDQRKKDILCDVTLIV 129

  Fly    39 EGQIVKAHRLVLSVCSPFFRKMFTQMPSNTHAIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPA 103
            |.:..:|||.||:.||.:|.:.......|...:.....|:......|:||.|..::.:.::.:..
Human   130 ERKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIRE 194

  Fly   104 FISTAESLQIKGLTDN---------------------DPAPQPPQESSPPPAAPHVQQQQ--IPA 145
            .|..||.|::..|.|:                     |.|.|.|.|.....|.....:::  :.:
Human   195 VIRCAEFLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRPHEDCENSAGEEEDEEEETMDS 259

  Fly   146 QRVQRQQPRASARYKIETVDDGLGDEKQSTTQIVIQTTAAPQATIVQQQQPQQAAQQIQSQQL-- 208
            :..:...||           |.:..|..|.....|......:|.:.:...|....:..:...|
Human   260 ETAKMACPR-----------DQMLPEPISFEAAAIPVAEKEEALLPEPDVPTDTKESSEKDALTQ 313

  Fly   209 ----------------QTGTTTTATLVSTNKRSAQRSSLTPASSSAGVKRSKTS--------TSA 249
                            ...:.:|:...||.:.....:||.|..:...:|....|        |..
Human   314 YPRYKKYQLACTKNVYNASSHSTSGFASTFREDNSSNSLKPGLARGQIKSEPPSEENEEESITLC 378

  Fly   250 NVMDPLDSTTETGATTTAQLVPQQITVQTSVVSAA--EAKLHQQSPQQVRQEEAEYIDLPMELPT 312
            ...|..|:....|.....:..|......|:...||  |......||..:|    ....:...:..
Human   379 LSGDEPDAKDRAGDVEMDRKQPSPAPTPTAPAGAACLERSRSVASPSCLR----SLFSITKSVEL 439

  Fly   313 KSEPDYSEDHGDAAGDAEGTYVEDDTYGDMRYDDSYFTEN---EDAGNQTAAN-TSGGGVTATTS 373
            ...|..|:.|  .|......:.:..|.||::.|.:.||.|   ...|.:..:| |.|..:.....
Human   440 SGLPSTSQQH--FARSPACPFDKGITQGDLKTDYTPFTGNYGQPHVGQKEVSNFTMGSPLRGPGL 502

  Fly   374 KAVVKQQSQNYSESSFVDTSG-DQGNTEAQAATSAS----------------------------- 408
            :|:.||:.:....|....:|. ||.:|...:.:..|
Human   503 EALCKQEGELDRRSVIFSSSACDQVSTSVHSYSGVSSLDKDLSEPVPKGLWVGAGQSLPSSQAYS 567

  Fly   409 -----ATKIPPRKRGRPKT------KVEDQTPKPKLLEKLQAATLNEEASEPAVYASTTKGGVKL 462
                 |..:|.|.  ||.|      ||..::|      .|:..|....:.....||....||...
Human   568 HGGLMADHLPGRM--RPNTSCPVPIKVCPRSP------PLETRTRTSSSCSSYSYAEDGSGGSPC 624

  Fly   463 IFNGHLFKFSFRKADYSVFQCCY------REHGE----------ECKVRVVCDQKRVFPYEGEHV 511
                     |....::|...|..      .||.|          :.:.::.|:|........|..
Human   625 ---------SLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESG 680

  Fly   512 HFMQASDKSCLPSQFMPGESGVISSLSPSKELLMKNTTKLEEADDKEDEDFEEFEIQEIDEIELD 576
            .|.:|..:|| |.|....|              :|....:::..|....||:          .:.
Human   681 SFSEADSESC-PVQDRGQE--------------VKLPFPVDQITDLPRNDFQ----------MMI 720

  Fly   577 EPEKTPAKEEEVDPNDFREKIKRRLQKALQNKKK 610
            :..|..:::.|. .:|.|.:.|.|:......|:|
Human   721 KMHKLTSEQLEF-IHDVRRRSKNRIAAQRCRKRK 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mod(mdg4)	NP_788698.1	BTB	22..118	CDD:279045	24/95 (25%)
		BTB	33..118	CDD:197585	23/84 (27%)
		FLYWCH	452..512	CDD:282369	13/75 (17%)
BACH2	XP_024302278.1	BTB	113..219	CDD:306997	25/105 (24%)
		bZIP_BACH	726..796	CDD:269867	7/29 (24%)
		coiled coil	730..792	CDD:269867	7/25 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	50	1.000	Inparanoid score	I5472
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050