DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mod(mdg4) and edc-3

DIOPT Version :9

Sequence 1:	NP_788698.1	Gene:	mod(mdg4) / 49228	FlyBaseID:	FBgn0002781	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_492328.1	Gene:	edc-3 / 172653	WormBaseID:	WBGene00011036	Length:	566	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	61/316 - (19%)
Similarity:	98/316 - (31%)	Gaps:	117/316 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 GTYVEDDTYGDMRYDDSYFTENEDAGNQTAANTSGGGVTA----TTSKAVVKQ--------QSQN 383
            |:.:..:|.....|.....|.:.:.||.|.||....|:..    |.|.:.:.:        ||..
Worm     7 GSVISTETKDGNVYQGKLTTYDTNNGNLTMANVIKNGLPLHRCFTLSSSDISRLKVIRGATQSTQ 71

  Fly   384 YSESSFVDTSGDQGNTE------------AQAATSASATKIPPRKRGR-----PKTKVEDQTPK- 430
            .|:...|..|.:..|.:            :.:..|:||:.:|...|.|     |:...:.::||
Worm    72 KSQPLPVQNSSNSVNKQRPLKKSAESTVSSTSTASSSASSVPDSSRNRSVAVSPQKSAKGRSPKK 136

  Fly   431 -PKLLEKLQAATLNEEASEPAVYASTTKGGVKLIFNGHLFKFSFRKADYSVFQCCYREHGEECKV 494
             ...:|||                                               :..|....|:
Worm   137 FATNVEKL-----------------------------------------------FEHHSTPSKL 154

  Fly   495 RVVCDQKRV------FPYEGEHV----HFMQASDKS----------------CLPSQFMPGESG- 532
            .:...|.|.      |.:..|.:    || |:.|:.                |...|   |.||
Worm   155 TLAKKQSRQSPMHNGFSHTAEEISATPHF-QSFDRQVPNPKVLSTIASNGGRCSKKQ---GPSGN 215

  Fly   533 -VISSLSPSKELLMKNTTKLEEADD---KEDEDFEE----FEIQEIDEIELDEPEK 580
             |:.:|:..|.:..:|...|.:..|   ..|.||.|    ||..|.|:...:..||
Worm   216 PVLDALNHYKGIGGRNKNDLADPIDFDLDSDFDFAENLKLFEKDENDDQYYETVEK 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mod(mdg4)	NP_788698.1	BTB	22..118	CDD:279045
		BTB	33..118	CDD:197585
		FLYWCH	452..512	CDD:282369	6/69 (9%)
edc-3	NP_492328.1	Sm_like	6..63	CDD:381907	12/55 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.788662	Normalized mean entropy	S7188
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950