DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cc and PHB5

DIOPT Version :9

Sequence 1:	NP_001163012.2	Gene:	l(2)37Cc / 49168	FlyBaseID:	FBgn0002031	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_196934.1	Gene:	PHB5 / 831280	AraportID:	AT5G14300	Length:	249	Species:	Arabidopsis thaliana

Alignment Length:	271	Identity:	130/271 - (47%)
Similarity:	185/271 - (68%)	Gaps:	31/271 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIR 70
            |.::. :|||.|:  ..|.|.::.|:||.|||:|.||.||.|..||||||..|||||:|.|||||
plant     6 FTKVA-LGLGAAI--AAVRSTMFTVDGGQRAVMFHRFEGILEEPVGEGTHRKIPWVQKPYIFDIR 67

  Fly    71 SQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFD 135
            ::|..:...:|:||||.||:|||:::|                          |:|:|||||||:
plant    68 TKPYKINTDSGTKDLQMVNLTLRVMFR--------------------------PDVVKAVVAQFN 106

  Fly   136 AGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVV 200
            |.||:|:|..||..:.:.|..|||:|..:|||:|:|.|::|:||:||||.|||||||||:::|||
plant   107 ADELLTERPQVSALIRETLIKRAKEFNIVLDDVSITGLSYGKEFSLAVERKQVAQQEAERSKFVV 171

  Fly   201 EKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQS 265
            .||:|::.|::|.|||::|||.:::|:...||.||::|||:|||.::|..||.|..|.|||||.:
plant   172 AKADQERRAAVIRAEGESEAARVISKATAGAGMGLIKLRRVEAAREVAITLSNSPNVVYLPSGGN 236

  Fly   266 TL--LNLPSTI 274
            .|  :|.||.:
plant   237 MLFAMNGPSKV 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cc	NP_001163012.2	SPFH_prohibitin	27..221	CDD:259799	96/193 (50%)
PHB5	NP_196934.1	SPFH_prohibitin	24..192	CDD:259799	96/193 (50%)
PHB5	NP_196934.1	PHB	24..158	CDD:214581	75/159 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3435
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I829
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2416
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23222
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940