DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cc and PHB6

DIOPT Version :9

Sequence 1:	NP_001163012.2	Gene:	l(2)37Cc / 49168	FlyBaseID:	FBgn0002031	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001077924.1	Gene:	PHB6 / 816575	AraportID:	AT2G20530	Length:	286	Species:	Arabidopsis thaliana

Alignment Length:	261	Identity:	138/261 - (52%)
Similarity:	186/261 - (71%)	Gaps:	6/261 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGVAVLGGV----VNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPR 74
            :...|:||:    ....||||:|||||::|:|..|||:.|..||||..|||.:||||:|:|::|.
plant    17 IAAVVIGGLSLYGATHTLYNVDGGHRAIVFNRLVGIKDKVYPEGTHLMIPWFERPIIYDVRAKPY 81

  Fly    75 NVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGEL 139
            .|...:||:|||.|.|.||:|.||:.||||::|..||::|.|||||||..|.|||||||::|.:|
plant    82 LVESTSGSRDLQMVKIGLRVLTRPMADQLPEVYRSLGENYRERVLPSIIHETLKAVVAQYNASQL 146

  Fly   140 ITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAE 204
            |||||.||:.:.:.||:||..|...|||:|:|.||||:|||.|:|.||||.||||:|:|:|||||
plant   147 ITQRESVSREIRKILTLRAANFHIALDDVSITGLTFGKEFTAAIEGKQVAAQEAERAKFIVEKAE 211

  Fly   205 QQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLN 269
            |.|.:::|.|||:|::|.|:.::... ....:.||:||||.:||..:|||....|| |....|||
plant   212 QDKRSAVIRAEGEAKSAQLIGQAIAN-NQAFLTLRKIEAAREIAQTISRSANKVYL-SSNDLLLN 274

  Fly   270 L 270
            |
plant   275 L 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cc	NP_001163012.2	SPFH_prohibitin	27..221	CDD:259799	115/193 (60%)
PHB6	NP_001077924.1	SPFH_prohibitin	34..228	CDD:259799	115/193 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	224	1.000	Domainoid score	I690
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830