Protein Alignment Phb1 and nphs2

DIOPT Version :10

• Sequence 1: NP_476607.2
• Gene: Phb1 / 49168
• FlyBaseID: FBgn0002031
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001018155.2
• Gene: nphs2 / 557914
• ZFINID: ZDB-GENE-051102-2
• Length: 391
• Species: Danio rerio
• Alignment Length: 257
• Identity: 60/257 - (23%)
• Similarity: 100/257 - (38%)
• Gaps: 61/257 - (23%)

  Fly    35 RAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVP---VITGSKDLQNVNITLRILY 96
            |||.|.....:|:...|.|..|::|::....|.|||.|...:|   |:|  |||....:|....|
Zfish   145 RAVKFRLGHLLKKRPRGPGLMFYLPFLDVCHIVDIRLQILKIPPHMVVT--KDLVCTEVTAVCYY 207

  Fly    97 R------------PIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQR 149
            |            .|||                |:.::....::.::|.....:::..|:.::|.
Zfish   208 RIENVSVCYSSFASIPD----------------VMQALTQVSVREILAHHAFNDILLDRKRIAQE 256

  Fly   150 VSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISA 214
            :...|.....::|..::...:      .|..|..|::.....|||        |.:|....:|:|
Zfish   257 IQVTLDSGTCRWGIKVEKAEI------EEINLPPELQHNFAVEAE--------ARRQAQVKVIAA 307

  Fly   215 EGDAEAAGLLAKSF-GEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQ-STLLNLPSTI 274
            ||:..|...|..|. ..:|..||...|:       .||..|     |.|.| :.:||:|..:
Zfish   308 EGEKAACEALKASVESVSGSPLVMHLRL-------LQLLHS-----LRSEQPAVVLNIPPDV 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phb1	NP_476607.2	SPFH_prohibitin	27..221	CDD:259799	44/200 (22%)
nphs2	NP_001018155.2	SPFH_like	134..356	CDD:473137	60/254 (24%)