Protein Alignment Phb1 and phb2

DIOPT Version :10

• Sequence 1: NP_476607.2
• Gene: Phb1 / 49168
• FlyBaseID: FBgn0002031
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001016551.1
• Gene: phb2 / 549305
• XenbaseID: XB-GENE-5844763
• Length: 301
• Species: Xenopus tropicalis
• Alignment Length: 280
• Identity: 142/280 - (50%)
• Similarity: 192/280 - (68%)
• Gaps: 19/280 - (6%)

  Fly     5 FFNRI--GQMGLGVA---VLGG-----VVNSALYNVEGGHRAVIFDRFTGIKEN-VVGEGTHFFI 58
            |..|:  |..|:|.|   :||.     .|..:::.|||||||:.|:|..|:::: ::.||.||..
 Frog     8 FAGRLPAGPRGMGTAMKLLLGAGAVAYAVKESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRF 72

  Fly    59 PWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIA 123
            ||.|.|||:|||::||.:...|||||||.||||||:|.||:..:||.:|..||.||||||||||.
 Frog    73 PWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIV 137

  Fly   124 PEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQV 188
            .||||:|||:|:|.:|||||..||..:.:|||.|||.|..||||:::|.|:|.||:|.|||.|||
 Frog   138 NEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQV 202

  Fly   189 AQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEA---GDGLVELRRIEAAEDIAYQ 250
            |||||::|:|:||||:|.:...|:.|||:|.|    ||..|:|   ..|.::||||.||:.||..
 Frog   203 AQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAA----AKMIGDALSKNPGYLKLRRIRAAQSIAKT 263

  Fly   251 LSRSRGVAYLPSGQSTLLNL 270
            ::.|:...|| :..|.:|||
 Frog   264 IASSQNRVYL-NADSLVLNL 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phb1	NP_476607.2	SPFH_prohibitin	27..221	CDD:259799	112/194 (58%)
phb2	NP_001016551.1	Necessary for transcriptional repression. /evidence=ECO:0000250	19..49		10/29 (34%)
		SPFH_prohibitin	40..235	CDD:259799	113/198 (57%)
		Necessary for transcriptional repression. /evidence=ECO:0000250	150..174		13/23 (57%)