Protein Alignment Phb1 and PHB1

DIOPT Version :10

• Sequence 1: NP_476607.2
• Gene: Phb1 / 49168
• FlyBaseID: FBgn0002031
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 204/271 - (75%)
• Similarity: 238/271 - (87%)
• Gaps: 0/271 - (0%)

  Fly     1 MAAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPI 65
            |||:.|..||:.||.:||.|||||||||||:.||||||||||.|:::.||||||||.|||||:||
Human     1 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPI 65

  Fly    66 IFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAV 130
            |||.||:|||||||||||||||||||||||:||:..|||:|:|.:|:||||||||||..|:||:|
Human    66 IFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSV 130

  Fly   131 VAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEK 195
            ||:|||||||||||:||::||.:||.||..||.||||:||||||||:|||.|||.|||||||||:
Human   131 VARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAER 195

  Fly   196 ARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYL 260
            ||||||||||||.|:|||||||::||.|:|.|...|||||:|||::||||||||||||||.:.||
Human   196 ARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYL 260

  Fly   261 PSGQSTLLNLP 271
            |:|||.||.||
Human   261 PAGQSVLLQLP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phb1	NP_476607.2	SPFH_prohibitin	27..221	CDD:259799	150/193 (78%)
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	150/193 (78%)