DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cc and phb

DIOPT Version :9

Sequence 1:	NP_001163012.2	Gene:	l(2)37Cc / 49168	FlyBaseID:	FBgn0002031	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_989038.1	Gene:	phb / 394635	XenbaseID:	XB-GENE-977670	Length:	272	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	203/271 - (74%)
Similarity:	243/271 - (89%)	Gaps:	0/271 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPI 65
            |||:.|..||::|||:||.|||||||||||:.||:|||||||.|::|.||||||||.|||||:||
Frog     1 MAARLFETIGKLGLGLAVAGGVVNSALYNVDAGHQAVIFDRFRGVQETVVGEGTHFLIPWVQKPI 65

  Fly    66 IFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAV 130
            |||.||:||||||:||||||||||||||||:||:.:|||:|:|.:|:||||||||||..|:||:|
Frog    66 IFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPMGNQLPRIFTSIGEDYDERVLPSITTEILKSV 130

  Fly   131 VAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEK 195
            ||:|||||||||||:||::||::|..||..||.||||:||||||||:|||.|||.|||||||||:
Frog   131 VARFDAGELITQRELVSRQVSEDLMERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAER 195

  Fly   196 ARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYL 260
            |||:||||||||.|::||||||::||.|:|.|..:|||||:|||::||||||||||||:|.|.||
Frog   196 ARFIVEKAEQQKKAAVISAEGDSKAAELIATSLADAGDGLIELRKLEAAEDIAYQLSRARNVTYL 260

  Fly   261 PSGQSTLLNLP 271
            ||||||||.||
Frog   261 PSGQSTLLQLP 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cc	NP_001163012.2	SPFH_prohibitin	27..221	CDD:259799	146/193 (76%)
phb	NP_989038.1	SPFH_prohibitin	27..221	CDD:259799	146/193 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	279	1.000	Domainoid score	I1679
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1980
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1800
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	1	1.000	-	-		FOG0003661
OrthoInspector	1	1.000	-	-		oto105174
Panther	1	1.100	-	-	LDO	PTHR23222
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R920
SonicParanoid	1	1.000	-	-		X2109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110