DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cc and phb

DIOPT Version :9

Sequence 1:	NP_001163012.2	Gene:	l(2)37Cc / 49168	FlyBaseID:	FBgn0002031	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_005163854.1	Gene:	phb / 321346	ZFINID:	ZDB-GENE-030131-6577	Length:	309	Species:	Danio rerio

Alignment Length:	269	Identity:	205/269 - (76%)
Similarity:	240/269 - (89%)	Gaps:	0/269 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIF 67
            |:.|..||::||.:|:.|||||||||||:.||||||||||.|:::.||||||||.|||||:||||
Zfish    40 AKLFESIGKLGLALAIGGGVVNSALYNVDAGHRAVIFDRFRGVQDVVVGEGTHFLIPWVQKPIIF 104

  Fly    68 DIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVA 132
            |.||:|||||||||||||||||||||||:||:..|||:|:|.:|:||||||||||..||||:|||
Zfish   105 DCRSRPRNVPVITGSKDLQNVNITLRILFRPVAGQLPRIFTSIGEDYDERVLPSITTEVLKSVVA 169

  Fly   133 QFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKAR 197
            :|||||||||||:||::||::||.||..||.||||:||||||||:|||.|||||||||||||:||
Zfish   170 RFDAGELITQRELVSRQVSEDLTERASTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERAR 234

  Fly   198 FVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPS 262
            ||||||||||.|:|||||||::||.|:|.|..||||||||||::|||||||:||||:|.|.||||
Zfish   235 FVVEKAEQQKQAAIISAEGDSQAALLIANSLAEAGDGLVELRKLEAAEDIAFQLSRARNVTYLPS 299

  Fly   263 GQSTLLNLP 271
            ||.|||.||
Zfish   300 GQGTLLQLP 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cc	NP_001163012.2	SPFH_prohibitin	27..221	CDD:259799	152/193 (79%)
phb	XP_005163854.1	PHB	63..224	CDD:214581	124/160 (78%)
phb	XP_005163854.1	SPFH_prohibitin	64..258	CDD:259799	152/193 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580326
Domainoid	1	1.000	285	1.000	Domainoid score	I1588
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1980
Inparanoid	1	1.050	411	1.000	Inparanoid score	I1841
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	1	1.000	-	-		FOG0003661
OrthoInspector	1	1.000	-	-		oto39293
orthoMCL	1	0.900	-	-		OOG6_101926
Panther	1	1.100	-	-	LDO	PTHR23222
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R920
SonicParanoid	1	1.000	-	-		X2109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.840