Protein Alignment Phb1 and STOML2

DIOPT Version :10

• Sequence 1: NP_476607.2
• Gene: Phb1 / 49168
• FlyBaseID: FBgn0002031
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_038470.1
• Gene: STOML2 / 30968
• HGNCID: 14559
• Length: 356
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 67/329 - (20%)
• Similarity: 120/329 - (36%)
• Gaps: 90/329 - (27%)

  Fly    13 GLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIP----W-VQRPIIFDIRSQ 72
            |.|..:|.|   |.|.:.....||     .:|:..|.|    ..|:|    | |:|...|....:
Human     8 GTGALLLRG---SLLASGRAPRRA-----SSGLPRNTV----VLFVPQQEAWVVERMGRFHRILE 60

  Fly    73 PR---NVPVITGSKDLQNV----------------NITLRI---LYRPIPDQLPKIYTILGQDYD 115
            |.   .:||:...:.:|::                |:||:|   ||..|.|.....|   |.:..
Human    61 PGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASY---GVEDP 122

  Fly   116 ERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFG-----FILDDISLTHLTF 175
            |..:..:|...:::.:.:....::..:||.::..:...:...|..:|     :.:.||.:..
Human   123 EYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPP--- 184

  Fly   176 GREFTLAVEMKQVAQQEAEKARFVVEK----------AEQQKLASIISAEGD---------AEAA 221
                .:...|:...:.|..|...|:|.          ||.:|.|.|:::|.:         .||:
Human   185 ----RVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEAS 245

  Fly   222 GLLAKSFGEA--------------GDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPS 272
            .:|||:..:|              ||....|...|.......:|::......|||...   ::.|
Human   246 AVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPG---DVTS 307

  Fly   273 TIAQ 276
            .:||
Human   308 MVAQ 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phb1	NP_476607.2	SPFH_prohibitin	27..221	CDD:259799	46/244 (19%)
STOML2	NP_038470.1	HflC	41..300	CDD:440099	50/268 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..356