DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cc and Phb

DIOPT Version :9

Sequence 1:	NP_001163012.2	Gene:	l(2)37Cc / 49168	FlyBaseID:	FBgn0002031	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_114039.1	Gene:	Phb / 25344	RGDID:	3322	Length:	272	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	205/271 - (75%)
Similarity:	238/271 - (87%)	Gaps:	0/271 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPI 65
            |||:.|..||:.||.:||.|||||||||||:.||||||||||.|:::.||||||||.|||||:||
  Rat     1 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPI 65

  Fly    66 IFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAV 130
            |||.||:|||||||||||||||||||||||:||:..|||:|||.:|:||||||||||..|:||:|
  Rat    66 IFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSV 130

  Fly   131 VAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEK 195
            ||:|||||||||||:||::||.:||.||..||.||||:||||||||:|||.|||.|||||||||:
  Rat   131 VARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAER 195

  Fly   196 ARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYL 260
            ||||||||||||.|:|||||||::||.|:|.|...|||||:|||::||||||||||||||.:.||
  Rat   196 ARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYL 260

  Fly   261 PSGQSTLLNLP 271
            |:|||.||.||
  Rat   261 PAGQSVLLQLP 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cc	NP_001163012.2	SPFH_prohibitin	27..221	CDD:259799	151/193 (78%)
Phb	NP_114039.1	SPFH_prohibitin	27..221	CDD:259799	151/193 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340526
Domainoid	1	1.000	283	1.000	Domainoid score	I1567
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1980
Inparanoid	1	1.050	411	1.000	Inparanoid score	I1803
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	1	1.000	-	-		FOG0003661
OrthoInspector	1	1.000	-	-		otm46246
orthoMCL	1	0.900	-	-		OOG6_101926
Panther	1	1.100	-	-	LDO	PTHR23222
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2109
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810