DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cc and mec-2

DIOPT Version :9

Sequence 1:	NP_001163012.2	Gene:	l(2)37Cc / 49168	FlyBaseID:	FBgn0002031	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001368712.1	Gene:	mec-2 / 180826	WormBaseID:	WBGene00003166	Length:	1239	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	56/248 - (22%)
Similarity:	100/248 - (40%)	Gaps:	40/248 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVP---VITGSKDLQNVNIT 91
            |:...|||||.....:.....|.|..|.:|.:......|:|.....||   ::  |||...|.:.
Worm   144 VQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDTYRKVDLRVLSFEVPPQEIL--SKDSVTVAVD 206

  Fly    92 LRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTV 156
            ..:.:| |.:....:..:   :...|....:|...|:.::......|:::.||.:|.::...|..
Worm   207 AVVYFR-ISNATISVTNV---EDAARSTKLLAQTTLRNILGTKTLAEMLSDREAISHQMQTTLDE 267

  Fly   157 RAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAA 221
            ..:.:|..::.:.:      ::..|.|::::....|||.||        :..|.:|.|||:.:|:
Worm   268 ATEPWGVKVERVEV------KDVRLPVQLQRAMAAEAEAAR--------EARAKVIVAEGEQKAS 318

  Fly   222 GLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPSTI 274
            ..|.                ||||.||...|..: :.||.:..|......|||
Worm   319 RALK----------------EAAEVIAESPSALQ-LRYLQTLNSISAEKNSTI 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cc	NP_001163012.2	SPFH_prohibitin	27..221	CDD:259799	41/193 (21%)
mec-2	NP_001368712.1	SPFH_stomatin	160..361	CDD:259801	50/232 (22%)
mec-2	NP_001368712.1	PTZ00121	<571..>913	CDD:173412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910