DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP89A5

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_176675.1	Gene:	CYP89A5 / 842803	AraportID:	AT1G64950	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	131/557 - (23%)
Similarity:	223/557 - (40%)	Gaps:	113/557 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IW------IFCATLLAILFGGVRKPKR--FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFAR 62
            ||      :|.:.||.:||..:|....  .||.|.::|.:|:   :..||..||    .::.:.|
plant     3 IWLLILGSLFLSLLLNLLFFRLRDSSSLPLPPDPNYFPFIGT---IQWLRQGLG----GLNNYLR 60

  Fly    63 QYVNPYG-FYGLKI-GKDKVVIAYTNDAISEMMTNEDI-DGRPD--------------------G 104
            ...:..| ...|:| .:..:.:|..:.|...::.|..: ..||.                    |
plant    61 SVHHRLGPIITLRITSRPSIFVADRSLAHQALVLNGAVFADRPPAAPISKIISSNQHNISSCLYG 125

  Fly   105 IFYRLRTFNSRLGVLLTDG-EMWVEQRRFILRHL-----KNFGFARSGMMDIVHNEATCLL---- 159
            ..:||...|....:|.... ..:...||::|..|     ||.|.....::|.:|.....||
plant   126 ATWRLLRRNLTSEILHPSRVRSYSHARRWVLEILFDRFGKNRGEEPIVVVDHLHYAMFALLVLMC 190

  Fly   160 --QDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLL-----ETFFELF 217
              ..|.:|.:|......|.::...:...:|| ||            |:.|:|:     |.||::.
plant   191 FGDKLDEKQIKQVEYVQRRQLLGFSRFNILN-LW------------PKFTKLILRKRWEEFFQMR 242

  Fly   218 KNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYL 282
            :.        .|..||    |........||..::    .|.|.|         ::.::.:.||:
plant   243 RE--------QHDVLL----PLIRARRKIVEERKN----RSSEEE---------EDNKEYVQSYV 282

  Fly   283 RA--QDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVG 345
            ..  :.|..|||...::..::::|.:....|::||..:|.:...:||..|:||:|.::|||.|||
plant   283 DTLLELELPDEKRKLNEDEIVSLCSEFLNGGTDTTATALQWIMANLVKNPDIQKRLYEEIKSVVG 347

  Fly   346 LERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLI 410
            .|.......|..|:||.||:.:|.:|......|.:||....||.|.||::||:..:......:..
plant   348 EEANEVEEEDAQKMPYLEAVVMEGLRRHPPGHFVLPHSVTEDTVLGGYKVPKNGTINFMVAEIGR 412

  Fly   411 NPVDFPDPESFNPDRYLFDGHLKLPEAFN----------PFGFGRHRCMGDLLGRQNLFMFTTTV 465
            :|..:.:|.:|.|:|:       :.||.:          |||.||..|.|..|...:|..:...:
plant   413 DPKVWEEPMAFKPERF-------MEEAVDITGSRGIKMMPFGAGRRICPGIGLAMLHLEYYVANM 470

  Fly   466 LQNFKMVAIPG-QVPEEVPLEGATAAVKPYDIMLVAR 501
            ::.|....:.| :|.....||.......|...:.|.|
plant   471 VREFDWKEVQGHEVDLTEKLEFTVVMKHPLKALAVPR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	118/504 (23%)
CYP89A5	NP_176675.1	CYP77_89	65..501	CDD:410698	111/480 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000