DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP89A7

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_176673.1	Gene:	CYP89A7 / 842801	AraportID:	AT1G64930	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	130/536 - (24%)
Similarity:	221/536 - (41%)	Gaps:	108/536 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IWIF------CATLLAILFGGVRKPKR--FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFAR 62
            ||:.      .:.||.:||..:|....  .||.|.::|.:|:   :..||..||.|    :.:.|
plant     3 IWLLILGSLSLSLLLNLLFFRLRDSSSLPLPPAPNFFPFLGT---LQWLRQGLGGF----NNYVR 60

  Fly    63 QYVNPYG-FYGLKI-GKDKVVIAYTNDAISEMMTNEDI--DGRPDGIFYRLRTFNSRLGVLLTDG 123
            ...:..| ...|:| .:..:.:|..:.|...::.|..:  |..|.....::.:.|.........|
plant    61 SVHHRLGPIITLRITSRPAIFVADGSLAHQALVLNGAVFADRPPAAPISKILSNNQHTITSCLYG 125

  Fly   124 EMWVEQRRFILR-----HLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDL-T 182
            ..|...||.|..     .:|::...|..:::|           |.|::.||||::..:....| .
plant   126 VTWRLLRRNITEILHPSRMKSYSHVRHWVLEI-----------LFDRLRKSGGEEPIVVFDHLHY 179

  Fly   183 SVYVLNTLWC-------------------MLSG-RRYEPGS--PEITQLL-----ETFFELFKNI 220
            :::.:..|.|                   ||.| .||...:  |:.|:|:     |.||::.:..
plant   180 AMFAVLVLMCFGDKLDEKQIKQVEYVQRQMLLGFARYSILNLCPKFTKLILRKRWEEFFQMRREQ 244

  Fly   221 DMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRA- 284
            ..|        |||.|...    ...||..:.    .|.|.|         :|.::.:.||:..
plant   245 QDV--------LLRLIYAR----RKIVEERKK----RSSEEE---------EENKEYVQSYVDTL 284

  Fly   285 -QDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLER 348
             ..|..|||...::..::::|.:..:|||:||...|.:...:||...|||||.::||..|||.|.
plant   285 LDVELPDEKRKLNEDEIVSLCSEFLIAGSDTTATVLQWIMANLVKNQEIQERLYEEITNVVGEEA 349

  Fly   349 IPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPV 413
            .....:|..|:||.:|:.:||:|........:||....||.|.||::||...:......:..:|.
plant   350 KVVEEKDTQKMPYLKAVVMEALRRHPPGNTVLPHSVTEDTVLGGYKVPKKGTINFLVAEIGRDPK 414

  Fly   414 DFPDPESFNPDRYLFDGHLKLPEAFN----------PFGFGRHRCMGDLLGRQNLFMFTTTVLQN 468
            .:.:|.:|.|:|::.:     .||.:          |||.||..|.|..|...:|..:...:::.
plant   415 VWEEPMAFKPERFMGE-----EEAVDITGSRGIKMMPFGAGRRICPGIGLAMLHLEYYVANMVRE 474

  Fly   469 FKMVAIPGQVPEEVPL 484
            |:...:.|   .||.|
plant   475 FQWKEVEG---HEVDL 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	120/500 (24%)
CYP89A7	NP_176673.1	CYP77_89	65..502	CDD:410698	112/467 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000