DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP78A5

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_172827.1	Gene:	CYP78A5 / 837932	AraportID:	AT1G13710	Length:	517	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	120/513 - (23%)
Similarity:	204/513 - (39%)	Gaps:	103/513 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFC-----KVIDVFARQ 63
            ||.::.....||..:.|..|.:...|||:     ||          |.:|.     :|:...|::
plant    30 TVAFLLSPGGLAWAWTGSSKSRVSIPGPS-----GS----------LSVFSGSNPHRVLAALAKR 79

  Fly    64 Y-VNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRP------DGIFYRLRTFNSRLGVLLT 121
            : .:|  .....:|..:.||:...:...|::::.....||      :.:|:|...|       ..
plant    80 FKASP--LMAFSVGFSRFVISSEPETAKEILSSSAFADRPVKESAYELLFHRAMGF-------AP 135

  Fly   122 DGEMWVEQRR------FILRHLKNFGFARSGM-MDIVHNEATCLLQDLKDKVLKSGGKQTRIEMH 179
            .||.|...||      |..|.:.:|...|.|: |.:|.          |.|.|.:......:|:.
plant   136 YGEYWRNLRRISSTHLFSPRRIASFEGVRVGIGMKMVK----------KIKSLVTSDACGEVEVK 190

  Fly   180 DLTSVYVLNTLWCMLSGRRYEPGSPE-----ITQLLETFFELFKNIDMVGALFS---HFPLLRFI 236
            .:.....||.:...:.|..|:.....     :.:|:...:||.       .:|:   ||..||:.
plant   191 KIVHFGSLNNVMTTVFGESYDFDEVNGKGCFLERLVSEGYELL-------GIFNWSDHFWFLRWF 248

  Fly   237 APNFSGYNGFVESHRSLY----TFMSKEIELHRLTYKN--YDEPRDLMDSYLRAQDEGNDEKGMF 295
                 .:.|..:..|:|.    ||:...||.|::...|  ..|..|.:|..|..|   .|||  .
plant   249 -----DFQGVRKRCRALVSEVNTFVGGIIEKHKMKKGNNLNGEENDFVDVLLGLQ---KDEK--L 303

  Fly   296 SDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLP 360
            ||..::|:..:|...|::|....:.:....:||..:||::.::||..............|..|||
plant   304 SDSDMIAVLWEMIFRGTDTVAILVEWVLARMVLHQDIQDKLYREIASATSNNIRSLSDSDIPKLP 368

  Fly   361 YCEAITLEAVRMFMLHTFGIP-----HRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPES 420
            |.:||..|.:|   ||..| |     ..|:.|..:....:|..|:.:.....:..|...:.|||:
plant   369 YLQAIVKETLR---LHPPG-PLLSWARLAIHDVHVGPNLVPAGTIAMVNMWSITHNAKIWTDPEA 429

  Fly   421 FNPDRYLFD------GHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMV 472
            |.|:|::.:      ..|:|.    |||.||..|.|..:|...:.::...::|||:.|
plant   430 FMPERFISEDVSIMGSDLRLA----PFGSGRRVCPGKAMGLATVHLWIGQLIQNFEWV 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	114/489 (23%)
CYP78A5	NP_172827.1	CYP78	81..505	CDD:410699	105/447 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000