Protein Alignment Cyp303a1 and Cyp2c23

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_114027.2
• Gene: Cyp2c23 / 83790
• RGDID: 620370
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 138/511 - (27%)
• Similarity: 254/511 - (49%)
• Gaps: 42/511 - (8%)

  Fly     5 VIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG 69
            |:.:.|.:||:: :..:|...|.||||...||:|:.||::         .|.|.....:....||
  Rat    12 VVSVTCLSLLSV-WTKLRTRGRLPPGPTPLPIIGNLLQLN---------LKDIPASLSKLAKEYG 66

  Fly    70 -FYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFI 133
             .|.|..|....|:.:..|.:.|.:..:..:....|....:...:...|::.::||.|...|||.
  Rat    67 PVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGYGLIFSNGERWKVMRRFS 131

  Fly   134 LRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYV---LNTLWCMLS 195
            |..|:|||..:..:.:.|..||.||:::|         ::|:.:..|.|.:..   .|.:..:|.
  Rat   132 LMTLRNFGMGKRSLEERVQEEARCLVEEL---------QKTKAQPFDPTFILACAPCNVICSILF 187

  Fly   196 GRRYEPGSPEITQLLETFFELFKNIDMVGA-LFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSK 259
            ..|::..:.....|::...:.|:.::.|.. :::.:|.:....|  ..:..|.:....:..|:.:
  Rat   188 NDRFQYNNKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLP--GKHIEFAKRIDDVKNFILE 250

  Fly   260 EIELHRLTYKNYD--EPRDLMDSYL-RAQDEGNDEKGMFSDQSLLAIC-LDMFLAGSETTNKSLG 320
            :::.|:   |:.|  .|||.:|.:| :.::|.::.|..|..:: ||:| .::|.||:|||:.:|.
  Rat   251 KVKEHQ---KSLDPANPRDYIDCFLSKIEEEKDNLKSEFHLEN-LAVCGSNLFTAGTETTSTTLR 311

  Fly   321 FCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAV 385
            |..:.|:..||:|.:..:|:..|:|..:.|. .:|:.||||.:|:..|..|...|....:||..|
  Rat   312 FGLLLLMKYPEVQAKVHEELDRVIGRHQPPS-MKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVV 375

  Fly   386 CDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCM 449
            .||:...|.|||.|.|:.....::::..:|.:||.|:|..:| .:|..|..:.|.||..|:..|:
  Rat   376 QDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRACV 440

  Fly   450 GDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAV----KPYDIMLVAR 501
            |:.|.|..||:|.||:||.|.:..:  ..|:::.::..|..:    .||.:.||.|
  Rat   441 GESLARMELFLFFTTLLQKFSLKTL--VEPKDLDIKPITTGIINLPPPYKLCLVPR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	118/441 (27%)
Cyp2c23	NP_114027.2	CYP2C-like	65..489	CDD:410758	118/441 (27%)